Coaxial Electrohydrodynamic Atomization for the Production of Drug-Loaded Micro/Nanoparticles

Coaxial Electrohydrodynamic Atomization for the Production of Drug-Loaded Micro/Nanoparticles

Coaxial electrohydrodynamic atomization (CEHDA) presents a promising technology for preparing drug-loaded micro/nanoparticles with core-shell structures. Recently, CEHDA has attracted tremendous attention based on its specific advantages, including precise control over particle size and size distrib...

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Bibliographic Details
Main Authors: Chuanpin Chen, Wenfang Liu, Ping Jiang, Tingting Hong
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Micromachines
Subjects:
micro/nanoparticles
coaxial electrohydrodynamic atomization
drug delivery
Online Access:https://www.mdpi.com/2072-666X/10/2/125
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spelling doaj-e17d0626ae5a4c06bc73f4e02c5cdd4f2020-11-25T02:00:08ZengMDPI AGMicromachines2072-666X2019-02-0110212510.3390/mi10020125mi10020125Coaxial Electrohydrodynamic Atomization for the Production of Drug-Loaded Micro/NanoparticlesChuanpin Chen0Wenfang Liu1Ping Jiang2Tingting Hong3School of Pharmaceutical Sciences, Central South University, Changsha, Hunan 410013, ChinaSchool of Pharmaceutical Sciences, Central South University, Changsha, Hunan 410013, ChinaSchool of Pharmaceutical Sciences, Central South University, Changsha, Hunan 410013, ChinaSchool of Pharmaceutical Sciences, Central South University, Changsha, Hunan 410013, ChinaCoaxial electrohydrodynamic atomization (CEHDA) presents a promising technology for preparing drug-loaded micro/nanoparticles with core-shell structures. Recently, CEHDA has attracted tremendous attention based on its specific advantages, including precise control over particle size and size distribution, reduced initial burst release and mild preparation conditions. Moreover, with different needles, CEHDA can produce a variety of drug-loaded micro/nanoparticles for drug delivery systems. In this review, we summarize recent advances in using double-layer structure, multilayer structure and multicomponent encapsulation strategies for developing micro/nanoparticles. The merits of applying multiplexed electrospray sources for high-throughput production are also highlighted.https://www.mdpi.com/2072-666X/10/2/125micro/nanoparticlescoaxial electrohydrodynamic atomizationdrug delivery
collection DOAJ
language English
format Article
sources DOAJ
author Chuanpin Chen
Wenfang Liu
Ping Jiang
Tingting Hong
spellingShingle Chuanpin Chen
Wenfang Liu
Ping Jiang
Tingting Hong
Coaxial Electrohydrodynamic Atomization for the Production of Drug-Loaded Micro/Nanoparticles
Micromachines
micro/nanoparticles
coaxial electrohydrodynamic atomization
drug delivery
author_facet Chuanpin Chen
Wenfang Liu
Ping Jiang
Tingting Hong
author_sort Chuanpin Chen
title Coaxial Electrohydrodynamic Atomization for the Production of Drug-Loaded Micro/Nanoparticles
title_short Coaxial Electrohydrodynamic Atomization for the Production of Drug-Loaded Micro/Nanoparticles
title_full Coaxial Electrohydrodynamic Atomization for the Production of Drug-Loaded Micro/Nanoparticles
title_fullStr Coaxial Electrohydrodynamic Atomization for the Production of Drug-Loaded Micro/Nanoparticles
title_full_unstemmed Coaxial Electrohydrodynamic Atomization for the Production of Drug-Loaded Micro/Nanoparticles
title_sort coaxial electrohydrodynamic atomization for the production of drug-loaded micro/nanoparticles
publisher MDPI AG
series Micromachines
issn 2072-666X
publishDate 2019-02-01
description Coaxial electrohydrodynamic atomization (CEHDA) presents a promising technology for preparing drug-loaded micro/nanoparticles with core-shell structures. Recently, CEHDA has attracted tremendous attention based on its specific advantages, including precise control over particle size and size distribution, reduced initial burst release and mild preparation conditions. Moreover, with different needles, CEHDA can produce a variety of drug-loaded micro/nanoparticles for drug delivery systems. In this review, we summarize recent advances in using double-layer structure, multilayer structure and multicomponent encapsulation strategies for developing micro/nanoparticles. The merits of applying multiplexed electrospray sources for high-throughput production are also highlighted.
topic micro/nanoparticles
coaxial electrohydrodynamic atomization
drug delivery
url https://www.mdpi.com/2072-666X/10/2/125
work_keys_str_mv AT chuanpinchen coaxialelectrohydrodynamicatomizationfortheproductionofdrugloadedmicronanoparticles
AT wenfangliu coaxialelectrohydrodynamicatomizationfortheproductionofdrugloadedmicronanoparticles
AT pingjiang coaxialelectrohydrodynamicatomizationfortheproductionofdrugloadedmicronanoparticles
AT tingtinghong coaxialelectrohydrodynamicatomizationfortheproductionofdrugloadedmicronanoparticles
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