Proteomic and Biological Analysis of an In Vitro Human Endothelial System in Response to Drug Anaphylaxis

Proteomic and Biological Analysis of an In Vitro Human Endothelial System in Response to Drug Anaphylaxis

Anaphylaxis is a life-threatening systemic hypersensitivity reaction. During anaphylaxis, mediator release by effector cells causes endothelial barrier breakdown, increasing vascular permeability and leakage of fluids, which may lead to tissue edema. Although endothelial cells (ECs) are key players...

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Bibliographic Details
Main Authors: Alma Yuste-Montalvo, Sergio Fernandez-Bravo, Tamara Oliva, Carlos Pastor-Vargas, Diana Betancor, María José Goikoetxea, José Julio Laguna, Juan Antonio López, Gloria Alvarez-Llamas, Javier Cuesta-Herranz, Marta Martin-Lorenzo, Vanesa Esteban
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
endothelium
anaphylaxis
proteomics
coagulation and complement systems
drug allergy
system biological analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.692569/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.692569/full

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