Chemical modification of the lectin of the marine coral Gerardia savaglia by marine quinone avarone

The quinone avarone, isolated from the marine sponge Dysidea avara, possesses the ability to chemically modify proteins. In this work, modification of lectin isolated from the coral Gerardia savaglia by avarone was examined. The techniques used for studying the modification were: SDS PAGE, isoelectr...

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Main Authors:	Pajić Ivana, Vujčić Zoran, Vujčić Miroslava, Novaković Irena, Sladić Dušan, Gašić Miroslav J.
Format:	Article
Language:	English
Published:	Serbian Chemical Society 2007-01-01
Series:	Journal of the Serbian Chemical Society
Subjects:	avarone quinone gerardia savaglia lectin covalent modification
Online Access:	http://www.doiserbia.nb.rs/img/doi/0352-5139/2007/0352-51390712271P.pdf

id	doaj-e18158034d9c4f2ab60a71cce4949575
record_format	Article
spelling	doaj-e18158034d9c4f2ab60a71cce49495752020-12-24T14:33:13ZengSerbian Chemical Society Journal of the Serbian Chemical Society0352-51391820-74212007-01-0172121271127410.2298/JSC0712271P0352-51390712271PChemical modification of the lectin of the marine coral Gerardia savaglia by marine quinone avaronePajić Ivana0Vujčić Zoran1Vujčić Miroslava2Novaković Irena3Sladić Dušan4Gašić Miroslav J.5Hemijski fakultet, BeogradHemijski fakultet, BeogradIHTM - Centar za hemiju, BeogradIHTM - Centar za hemiju, BeogradHemijski fakultet, BeogradHemijski fakultet, BeogradThe quinone avarone, isolated from the marine sponge Dysidea avara, possesses the ability to chemically modify proteins. In this work, modification of lectin isolated from the coral Gerardia savaglia by avarone was examined. The techniques used for studying the modification were: SDS PAGE, isoelectric focusing and hemagglutination testing. The results of the SDS PAGE indicate dimerization of the protein. A shift of the pI toward lower value occurs upon modification. The change of the hemagglutination activity of the protein confirms that chemical modification of G. savaglia lectin by avarone changes its ability to interact with the membrane of erythrocytes.http://www.doiserbia.nb.rs/img/doi/0352-5139/2007/0352-51390712271P.pdfavaronequinonegerardia savaglia lectincovalent modification
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Pajić Ivana Vujčić Zoran Vujčić Miroslava Novaković Irena Sladić Dušan Gašić Miroslav J.
spellingShingle	Pajić Ivana Vujčić Zoran Vujčić Miroslava Novaković Irena Sladić Dušan Gašić Miroslav J. Chemical modification of the lectin of the marine coral Gerardia savaglia by marine quinone avarone Journal of the Serbian Chemical Society avarone quinone gerardia savaglia lectin covalent modification
author_facet	Pajić Ivana Vujčić Zoran Vujčić Miroslava Novaković Irena Sladić Dušan Gašić Miroslav J.
author_sort	Pajić Ivana
title	Chemical modification of the lectin of the marine coral Gerardia savaglia by marine quinone avarone
title_short	Chemical modification of the lectin of the marine coral Gerardia savaglia by marine quinone avarone
title_full	Chemical modification of the lectin of the marine coral Gerardia savaglia by marine quinone avarone
title_fullStr	Chemical modification of the lectin of the marine coral Gerardia savaglia by marine quinone avarone
title_full_unstemmed	Chemical modification of the lectin of the marine coral Gerardia savaglia by marine quinone avarone
title_sort	chemical modification of the lectin of the marine coral gerardia savaglia by marine quinone avarone
publisher	Serbian Chemical Society
series	Journal of the Serbian Chemical Society
issn	0352-5139 1820-7421
publishDate	2007-01-01
description	The quinone avarone, isolated from the marine sponge Dysidea avara, possesses the ability to chemically modify proteins. In this work, modification of lectin isolated from the coral Gerardia savaglia by avarone was examined. The techniques used for studying the modification were: SDS PAGE, isoelectric focusing and hemagglutination testing. The results of the SDS PAGE indicate dimerization of the protein. A shift of the pI toward lower value occurs upon modification. The change of the hemagglutination activity of the protein confirms that chemical modification of G. savaglia lectin by avarone changes its ability to interact with the membrane of erythrocytes.
topic	avarone quinone gerardia savaglia lectin covalent modification
url	http://www.doiserbia.nb.rs/img/doi/0352-5139/2007/0352-51390712271P.pdf
work_keys_str_mv	AT pajicivana chemicalmodificationofthelectinofthemarinecoralgerardiasavagliabymarinequinoneavarone AT vujciczoran chemicalmodificationofthelectinofthemarinecoralgerardiasavagliabymarinequinoneavarone AT vujcicmiroslava chemicalmodificationofthelectinofthemarinecoralgerardiasavagliabymarinequinoneavarone AT novakovicirena chemicalmodificationofthelectinofthemarinecoralgerardiasavagliabymarinequinoneavarone AT sladicdusan chemicalmodificationofthelectinofthemarinecoralgerardiasavagliabymarinequinoneavarone AT gasicmiroslavj chemicalmodificationofthelectinofthemarinecoralgerardiasavagliabymarinequinoneavarone
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Chemical modification of the lectin of the marine coral Gerardia savaglia by marine quinone avarone

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