CysLT(1)R antagonists inhibit tumor growth in a xenograft model of colon cancer.
The expression of the inflammatory G-protein coupled receptor CysLT1R has been shown to be upregulated in colon cancer patients and associated with poor prognosis. The present study investigated the correlation between CysLT1R and colon cancer development in vivo using CysLT1R antagonists (ZM198,615...
Main Authors: | Sayeh Savari, Minghui Liu, Yuan Zhang, Wondossen Sime, Anita Sjölander |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3764114?pdf=render |
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