Alterations in Some Biochemical Parameters and Trace Elements in Asthmatic Patients in Owerri
Background:Asthma is a chronic disease characterized by recurrent cough and wheeze. Aim and Objectives: To determine the level of some biochemical parameters and trace elements in asthmatic patients attending General Hospital Owerri. Material and Methods: Thirty six confirmed asthmatic patients...
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Krishna Institute of Medical Sciences University
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doaj-e18b92c2dbd3421799b332e5a61302612020-11-24T21:29:54ZengKrishna Institute of Medical Sciences UniversityJournal of Krishna Institute of Medical Sciences University2231-42612231-42612017-04-01625156Alterations in Some Biochemical Parameters and Trace Elements in Asthmatic Patients in OwerriNnodim Johnkennedy0Nwadike Constance1Nwobodo Emmanuel2Edward Ukamaka3Aloy-Amadi Oluchi4Onah Christian5Department of Medical Laboratory Science, Faculty of Health Science, Imo State University Owerri, Imo State, NigeriaDepartment of Medical Laboratory Science, Faculty of Health Science, Imo State University Owerri, Imo State, NigeriaDepartment of Biochemistry, Chukwuemeka Odumegwu Ojukwu University Uli Anambra State NigeriaDepartment of Medical Laboratory Science, Faculty of Health Science, Imo State University Owerri, Imo State, NigeriaDepartment of Medical Laboratory Science, Faculty of Health Science, Imo State University Owerri, Imo State, NigeriaNnamdiAzikiwe University Teaching Hospital Nnewi Anambra State NigeriaBackground:Asthma is a chronic disease characterized by recurrent cough and wheeze. Aim and Objectives: To determine the level of some biochemical parameters and trace elements in asthmatic patients attending General Hospital Owerri. Material and Methods: Thirty six confirmed asthmatic patients and thirty six apparently healthy subjects (control) between the age of 10 to 30 years were selected in this study. Serum trace elements: Zinc and copper, malondialdehyde, vitamin C, vitamin E, immunoglobulin A and immunoglobulin E were estimated using standard methods. Results: There serum levels of copper, IgE, IgA and MDA were significantly increased in asthmatic patients when compared to control (p<0.05). While the serum levels of zinc, vitamin C and vitamin E were significantly decreased in asthmatic patients when compared with the control (P< 0.05). Conclusion: These observations probably indicated that asthmatic patients could be prone to the oxidative stress. Also, foods or diets containing antioxidants could be beneficial to asthmatic patients.http://www.jkimsu.com/jkimsu-vol6no2/JKIMSU,%20Vol.%206,%20No.%202,%20April-June%202017%20Page%2051-56.pdfTrace ElementsAsthmaAntioxidantsImunoglobulins |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nnodim Johnkennedy Nwadike Constance Nwobodo Emmanuel Edward Ukamaka Aloy-Amadi Oluchi Onah Christian |
spellingShingle |
Nnodim Johnkennedy Nwadike Constance Nwobodo Emmanuel Edward Ukamaka Aloy-Amadi Oluchi Onah Christian Alterations in Some Biochemical Parameters and Trace Elements in Asthmatic Patients in Owerri Journal of Krishna Institute of Medical Sciences University Trace Elements Asthma Antioxidants Imunoglobulins |
author_facet |
Nnodim Johnkennedy Nwadike Constance Nwobodo Emmanuel Edward Ukamaka Aloy-Amadi Oluchi Onah Christian |
author_sort |
Nnodim Johnkennedy |
title |
Alterations in Some Biochemical Parameters and Trace Elements in Asthmatic Patients in Owerri |
title_short |
Alterations in Some Biochemical Parameters and Trace Elements in Asthmatic Patients in Owerri |
title_full |
Alterations in Some Biochemical Parameters and Trace Elements in Asthmatic Patients in Owerri |
title_fullStr |
Alterations in Some Biochemical Parameters and Trace Elements in Asthmatic Patients in Owerri |
title_full_unstemmed |
Alterations in Some Biochemical Parameters and Trace Elements in Asthmatic Patients in Owerri |
title_sort |
alterations in some biochemical parameters and trace elements in asthmatic patients in owerri |
publisher |
Krishna Institute of Medical Sciences University |
series |
Journal of Krishna Institute of Medical Sciences University |
issn |
2231-4261 2231-4261 |
publishDate |
2017-04-01 |
description |
Background:Asthma is a chronic disease characterized
by recurrent cough and wheeze. Aim and Objectives:
To determine the level of some biochemical parameters
and trace elements in asthmatic patients attending
General Hospital Owerri. Material and Methods:
Thirty six confirmed asthmatic patients and thirty six
apparently healthy subjects (control) between the age
of 10 to 30 years were selected in this study. Serum
trace elements: Zinc and copper, malondialdehyde,
vitamin C, vitamin E, immunoglobulin A and
immunoglobulin E were estimated using standard
methods. Results: There serum levels of copper, IgE,
IgA and MDA were significantly increased in
asthmatic patients when compared to control (p<0.05).
While the serum levels of zinc, vitamin C and vitamin
E were significantly decreased in asthmatic patients
when compared with the control (P< 0.05).
Conclusion: These observations probably indicated
that asthmatic patients could be prone to the oxidative
stress. Also, foods or diets containing antioxidants
could be beneficial to asthmatic patients. |
topic |
Trace Elements Asthma Antioxidants Imunoglobulins |
url |
http://www.jkimsu.com/jkimsu-vol6no2/JKIMSU,%20Vol.%206,%20No.%202,%20April-June%202017%20Page%2051-56.pdf |
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