Eosinophilic gastroenteritis: a case report and review of the literature

• Main Authors: Paolo Biagi, Luigi Abate, Carmine Mellone, Stefania Salvadori, Andrea Peccetti, Alessandro Ginori
• Format: Article
• Language: English
• Published: PAGEPress Publications 2012-12-01
• Series: Italian Journal of Medicine
• Subjects: Eosinophilic gastrointestinal diseases; Eosinophilic gastroenteritis; Eosinophilia
• Online Access: http://www.italjmed.org/index.php/ijm/article/view/39

<p>Background<br />Eosinophilic gastroenteritis (EoG) is a rare disease of unknown etiology characterized by patchy or diffuse eosinophilic infiltration of the gastrointestinal tract wall. As clinical presentation and endoscopic/ radiological findings are nonspecific, diagnosis may only be ascertained by histologic findings.</p><p>Clinical case <br />This article presents a case of EoG with associated colonic involvement but without peripheral eosinophilia. Although no allergy could be demonstrated, the clinical symptoms and histologic pattern of diffuse eosinophilic mucosal infiltration disappeared after steroid therapy, as discovered by a careful endoscopic follow-up.</p><p>Discussion <br />Current concepts of this complex disorder and a review of the literature are presented.</p>