Malignant Peripheral Nerve Sheath Tumor of the Inguinum and Angiosarcoma of the Scalp in a Child with Neurofibromatosis Type 1

Benign and malignant tumors are common in the setting of neurofibromatosis type 1 (NF1). Malignant peripheral nerve sheath tumor (MPNST) and angiosarcoma are rare tumors in children and adolescents and mostly occur in young patients in relation to NF1. Both histological types can be present in the s...

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Main Authors: Marija Milković Periša, Tihana Džombeta, Jasminka Stepan Giljević, Božo Krušlin
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2017/7542825
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spelling doaj-e199c5126bda46999fc4bb50b0edbefb2020-11-24T23:27:20ZengHindawi LimitedCase Reports in Pathology2090-67812090-679X2017-01-01201710.1155/2017/75428257542825Malignant Peripheral Nerve Sheath Tumor of the Inguinum and Angiosarcoma of the Scalp in a Child with Neurofibromatosis Type 1Marija Milković Periša0Tihana Džombeta1Jasminka Stepan Giljević2Božo Krušlin3Institute of Pathology, School of Medicine, University of Zagreb, Šalata 10, 10000 Zagreb, CroatiaInstitute of Pathology, School of Medicine, University of Zagreb, Šalata 10, 10000 Zagreb, CroatiaDepartment of Oncology and Hematology “Mladen Ćepulić”, Children’s Hospital Zagreb, Klaićeva 16, 10000 Zagreb, CroatiaInstitute of Pathology, School of Medicine, University of Zagreb, Šalata 10, 10000 Zagreb, CroatiaBenign and malignant tumors are common in the setting of neurofibromatosis type 1 (NF1). Malignant peripheral nerve sheath tumor (MPNST) and angiosarcoma are rare tumors in children and adolescents and mostly occur in young patients in relation to NF1. Both histological types can be present in the same tumor mass in patients with NF1. We present a case of 12.5-year-old girl with NF1 who first presented with MPNST of the right inguinal region and 1.5 years later with unrelated angiosarcoma of the scalp.http://dx.doi.org/10.1155/2017/7542825
collection DOAJ
language English
format Article
sources DOAJ
author Marija Milković Periša
Tihana Džombeta
Jasminka Stepan Giljević
Božo Krušlin
spellingShingle Marija Milković Periša
Tihana Džombeta
Jasminka Stepan Giljević
Božo Krušlin
Malignant Peripheral Nerve Sheath Tumor of the Inguinum and Angiosarcoma of the Scalp in a Child with Neurofibromatosis Type 1
Case Reports in Pathology
author_facet Marija Milković Periša
Tihana Džombeta
Jasminka Stepan Giljević
Božo Krušlin
author_sort Marija Milković Periša
title Malignant Peripheral Nerve Sheath Tumor of the Inguinum and Angiosarcoma of the Scalp in a Child with Neurofibromatosis Type 1
title_short Malignant Peripheral Nerve Sheath Tumor of the Inguinum and Angiosarcoma of the Scalp in a Child with Neurofibromatosis Type 1
title_full Malignant Peripheral Nerve Sheath Tumor of the Inguinum and Angiosarcoma of the Scalp in a Child with Neurofibromatosis Type 1
title_fullStr Malignant Peripheral Nerve Sheath Tumor of the Inguinum and Angiosarcoma of the Scalp in a Child with Neurofibromatosis Type 1
title_full_unstemmed Malignant Peripheral Nerve Sheath Tumor of the Inguinum and Angiosarcoma of the Scalp in a Child with Neurofibromatosis Type 1
title_sort malignant peripheral nerve sheath tumor of the inguinum and angiosarcoma of the scalp in a child with neurofibromatosis type 1
publisher Hindawi Limited
series Case Reports in Pathology
issn 2090-6781
2090-679X
publishDate 2017-01-01
description Benign and malignant tumors are common in the setting of neurofibromatosis type 1 (NF1). Malignant peripheral nerve sheath tumor (MPNST) and angiosarcoma are rare tumors in children and adolescents and mostly occur in young patients in relation to NF1. Both histological types can be present in the same tumor mass in patients with NF1. We present a case of 12.5-year-old girl with NF1 who first presented with MPNST of the right inguinal region and 1.5 years later with unrelated angiosarcoma of the scalp.
url http://dx.doi.org/10.1155/2017/7542825
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AT jasminkastepangiljevic malignantperipheralnervesheathtumoroftheinguinumandangiosarcomaofthescalpinachildwithneurofibromatosistype1
AT bozokruslin malignantperipheralnervesheathtumoroftheinguinumandangiosarcomaofthescalpinachildwithneurofibromatosistype1
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