The Differential Roles for Neurodevelopmental and Neuroendocrine Genes in Shaping GnRH Neuron Physiology and Deficiency
Gonadotropin releasing hormone (GnRH) neurons are hypothalamic neuroendocrine cells that control sexual reproduction. During embryonic development, GnRH neurons migrate from the nose to the hypothalamus, where they receive inputs from several afferent neurons, following the axonal scaffold patterned...
Main Authors: | Roberto Oleari, Valentina Massa, Anna Cariboni, Antonella Lettieri |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/17/9425 |
Similar Items
-
Predictive factors for pituitary response to pulsatile GnRH therapy in patients with congenital hypogonadotropic hypogonadism
by: Jiang-Feng Mao, et al.
Published: (2018-01-01) -
Next-generation sequencing refines the genetic architecture of Greek GnRH-deficient patients
by: M I Stamou, et al.
Published: (2019-04-01) -
GnRH-1 Neural Migration From the Nose to the Brain Is Independent From Slit2, Robo3 and NELL2 Signaling
by: Ed Zandro M. Taroc, et al.
Published: (2019-03-01) -
Corrigendum: GnRH-1 Neural Migration From the Nose to the Brain Is Independent From Slit2, Robo3 and NELL2 Signaling
by: Ed Zandro M. Taroc, et al.
Published: (2019-04-01) -
Fgf8-deficient mice compensate for reduced GnRH neuronal population and exhibit normal testicular function
by: Wei eZhang, et al.
Published: (2015-09-01)