NEW PYRAN OF AN ENDOPHYTIC FUNGUS <i>Fusarium</i> sp. ISOLATED FROM THE LEAVES OF BROTOWALI (<i>Tinaspora crispa</i>)
Endophytes are microorganisms that reside asymptomatically in the tissues of higher plants and are relatively unstudied and a promising source of novel organic natural metabolites exhibiting a variety of biological activities. As a part of our systematic search for new bioactive lead structures from...
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doaj-e1d522c1e9844d8f971e1fe381809a9c2020-11-24T21:19:11ZengUniversitas Gadjah MadaIndonesian Journal of Chemistry1411-94202460-15782013-12-0113320921510.22146/ijc.2127814376NEW PYRAN OF AN ENDOPHYTIC FUNGUS <i>Fusarium</i> sp. ISOLATED FROM THE LEAVES OF BROTOWALI (<i>Tinaspora crispa</i>)Elfita Elfita0Munawar Munawar1Muharni Muharni2Suprayetno Suprayetno3Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera 30662Department of Biology, Faculty of Mathematics and Natural Sciences, Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera 30662Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera 30662Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera 30662Endophytes are microorganisms that reside asymptomatically in the tissues of higher plants and are relatively unstudied and a promising source of novel organic natural metabolites exhibiting a variety of biological activities. As a part of our systematic search for new bioactive lead structures from endophytic, the endophytic fungus Fusarium sp. isolated from the leaves of Brotowali (Tinaspora crispa), was cultured for isolation of metabolite. The endophytic fungus was cultivated on 6 L of Potatos Dextose Broth (PDB) medium at room temperature (no shaking) for 8 weeks. The cultures were then extracted with ethyl acetate to afford 9.4 g of residue after removal of the solvent under reduced pressure. The extract was separated into the fractions by column chromatography (CC) on silica gel. The fractions were further separated by silica gel column chromatography to give one compound. The molecular structure was established on the basis of spectroscopic analysis including UV, IR, 1H-NMR, 13C-NMR, HMQC, HMBC, COSY, and MS. The compound was determined as a new pyran.https://jurnal.ugm.ac.id/ijc/article/view/21278new pyranendophytic fungusFusarium sp.Tinaspora crispa |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Elfita Elfita Munawar Munawar Muharni Muharni Suprayetno Suprayetno |
spellingShingle |
Elfita Elfita Munawar Munawar Muharni Muharni Suprayetno Suprayetno NEW PYRAN OF AN ENDOPHYTIC FUNGUS <i>Fusarium</i> sp. ISOLATED FROM THE LEAVES OF BROTOWALI (<i>Tinaspora crispa</i>) Indonesian Journal of Chemistry new pyran endophytic fungus Fusarium sp. Tinaspora crispa |
author_facet |
Elfita Elfita Munawar Munawar Muharni Muharni Suprayetno Suprayetno |
author_sort |
Elfita Elfita |
title |
NEW PYRAN OF AN ENDOPHYTIC FUNGUS <i>Fusarium</i> sp. ISOLATED FROM THE LEAVES OF BROTOWALI (<i>Tinaspora crispa</i>) |
title_short |
NEW PYRAN OF AN ENDOPHYTIC FUNGUS <i>Fusarium</i> sp. ISOLATED FROM THE LEAVES OF BROTOWALI (<i>Tinaspora crispa</i>) |
title_full |
NEW PYRAN OF AN ENDOPHYTIC FUNGUS <i>Fusarium</i> sp. ISOLATED FROM THE LEAVES OF BROTOWALI (<i>Tinaspora crispa</i>) |
title_fullStr |
NEW PYRAN OF AN ENDOPHYTIC FUNGUS <i>Fusarium</i> sp. ISOLATED FROM THE LEAVES OF BROTOWALI (<i>Tinaspora crispa</i>) |
title_full_unstemmed |
NEW PYRAN OF AN ENDOPHYTIC FUNGUS <i>Fusarium</i> sp. ISOLATED FROM THE LEAVES OF BROTOWALI (<i>Tinaspora crispa</i>) |
title_sort |
new pyran of an endophytic fungus <i>fusarium</i> sp. isolated from the leaves of brotowali (<i>tinaspora crispa</i>) |
publisher |
Universitas Gadjah Mada |
series |
Indonesian Journal of Chemistry |
issn |
1411-9420 2460-1578 |
publishDate |
2013-12-01 |
description |
Endophytes are microorganisms that reside asymptomatically in the tissues of higher plants and are relatively unstudied and a promising source of novel organic natural metabolites exhibiting a variety of biological activities. As a part of our systematic search for new bioactive lead structures from endophytic, the endophytic fungus Fusarium sp. isolated from the leaves of Brotowali (Tinaspora crispa), was cultured for isolation of metabolite. The endophytic fungus was cultivated on 6 L of Potatos Dextose Broth (PDB) medium at room temperature (no shaking) for 8 weeks. The cultures were then extracted with ethyl acetate to afford 9.4 g of residue after removal of the solvent under reduced pressure. The extract was separated into the fractions by column chromatography (CC) on silica gel. The fractions were further separated by silica gel column chromatography to give one compound. The molecular structure was established on the basis of spectroscopic analysis including UV, IR, 1H-NMR, 13C-NMR, HMQC, HMBC, COSY, and MS. The compound was determined as a new pyran. |
topic |
new pyran endophytic fungus Fusarium sp. Tinaspora crispa |
url |
https://jurnal.ugm.ac.id/ijc/article/view/21278 |
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