Effects of single and multiple transplantations of human umbilical cord mesenchymal stem cells on the recovery of ovarian function in the treatment of premature ovarian failure in mice

Effects of single and multiple transplantations of human umbilical cord mesenchymal stem cells on the recovery of ovarian function in the treatment of premature ovarian failure in mice

Abstract Background Currently, there is no effective treatment for premature ovarian failure (POF), and stem cell therapy is considered the most promising treatment. Human umbilical cord blood mesenchymal stem cells (hUC-MSCs) have shown good regenerative ability in various diseases, including POF;...

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Bibliographic Details
Main Authors: Xiaodan Lv, Chunyi Guan, Ying Li, Xing Su, Lu Zhang, Xueqin Wang, Hong-Fei Xia, Xu Ma
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Ovarian Research
Subjects:
Premature ovarian failure
hUC-MSCs
Transplantation
Ovarian function
Online Access:https://doi.org/10.1186/s13048-021-00871-4

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