Analysis on degree distribution of tumor signaling networks

Tumorigenesis is a multi-factorial and multi-step process, among which the changes in cell signaling pathways play a key role. Up till now there are fewer studies on network structure of tumor signaling pathways. In present study the degree distribution was analyzed based on thirty kinds of tumor si...

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Main Authors:	JingQiu Huang, WenJun Zhang
Format:	Article
Language:	English
Published:	International Academy of Ecology and Environmental Sciences 2012-09-01
Series:	Network Biology
Subjects:	tumor cancer signaling pathway network degree distribution
Online Access:	http://www.iaees.org/publications/journals/nb/articles/2012-2(3)/analysis-on-degree-distribution-of-tumor-signaling-networks.pdf

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spelling	doaj-e1f3c56b1cd241b0b0554c9d0a9981b22020-11-24T21:39:06ZengInternational Academy of Ecology and Environmental SciencesNetwork Biology2220-88792012-09-012395109Analysis on degree distribution of tumor signaling networksJingQiu HuangWenJun ZhangTumorigenesis is a multi-factorial and multi-step process, among which the changes in cell signaling pathways play a key role. Up till now there are fewer studies on network structure of tumor signaling pathways. In present study the degree distribution was analyzed based on thirty kinds of tumor signaling networks, including VEGF-pathway, JNK-pathway, p53-signaling, etc. The results showed that almost all of them were scale-free complex networks. Key metabolites in some tumor networks were also described.http://www.iaees.org/publications/journals/nb/articles/2012-2(3)/analysis-on-degree-distribution-of-tumor-signaling-networks.pdftumorcancersignaling pathwaynetworkdegree distribution
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	JingQiu Huang WenJun Zhang
spellingShingle	JingQiu Huang WenJun Zhang Analysis on degree distribution of tumor signaling networks Network Biology tumor cancer signaling pathway network degree distribution
author_facet	JingQiu Huang WenJun Zhang
author_sort	JingQiu Huang
title	Analysis on degree distribution of tumor signaling networks
title_short	Analysis on degree distribution of tumor signaling networks
title_full	Analysis on degree distribution of tumor signaling networks
title_fullStr	Analysis on degree distribution of tumor signaling networks
title_full_unstemmed	Analysis on degree distribution of tumor signaling networks
title_sort	analysis on degree distribution of tumor signaling networks
publisher	International Academy of Ecology and Environmental Sciences
series	Network Biology
issn	2220-8879
publishDate	2012-09-01
description	Tumorigenesis is a multi-factorial and multi-step process, among which the changes in cell signaling pathways play a key role. Up till now there are fewer studies on network structure of tumor signaling pathways. In present study the degree distribution was analyzed based on thirty kinds of tumor signaling networks, including VEGF-pathway, JNK-pathway, p53-signaling, etc. The results showed that almost all of them were scale-free complex networks. Key metabolites in some tumor networks were also described.
topic	tumor cancer signaling pathway network degree distribution
url	http://www.iaees.org/publications/journals/nb/articles/2012-2(3)/analysis-on-degree-distribution-of-tumor-signaling-networks.pdf
work_keys_str_mv	AT jingqiuhuang analysisondegreedistributionoftumorsignalingnetworks AT wenjunzhang analysisondegreedistributionoftumorsignalingnetworks
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Analysis on degree distribution of tumor signaling networks

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