Editorial Comments to the Special Issue: “<i>Aggregaterbacter actinomycetemcomitans</i>—Gram-Negative Bacterial Pathogen”

Editorial Comments to the Special Issue: “<i>Aggregaterbacter actinomycetemcomitans</i>—Gram-Negative Bacterial Pathogen”

<i>Aggregatibacter actinomycetemcomitans</i> is a periodontal pathogen colonizing the oral cavity in many individuals of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade the host inflammatory response. Both harmless...

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Bibliographic Details
Main Authors: Jan Oscarsson, Joseph DiRienzo, Anders Johansson
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pathogens
Subjects:
Aggregatibacter actinomycetemcomitans
leukotoxin
cytolethal distending toxin
lipopolysaccharides
cytokine binding factors
horizontal gene transfer
Online Access:https://www.mdpi.com/2076-0817/9/6/441
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spelling doaj-e2044502811a44b4b0d006403b8e48062020-11-25T03:13:16ZengMDPI AGPathogens2076-08172020-06-01944144110.3390/pathogens9060441Editorial Comments to the Special Issue: “<i>Aggregaterbacter actinomycetemcomitans</i>—Gram-Negative Bacterial Pathogen”Jan Oscarsson0Joseph DiRienzo1Anders Johansson2Department of Odontology, Umeå University, S-901 87 Umeå, SwedenDepartment of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104-6030, USADepartment of Odontology, Umeå University, S-901 87 Umeå, Sweden<i>Aggregatibacter actinomycetemcomitans</i> is a periodontal pathogen colonizing the oral cavity in many individuals of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade the host inflammatory response. Both harmless and highly virulent genotypes of the bacterium have emerged because of the large genetic diversity within the species. The oral condition and age, as well as the geographic origin of the individual, influence the risk to be colonized by a virulent genotype of the bacterium. In the present editorial, the different genetic and virulence properties of <i>A. actinomycetemcomitans</i> will be addressed in relation to the publications in this Special Issue.https://www.mdpi.com/2076-0817/9/6/441Aggregatibacter actinomycetemcomitansleukotoxincytolethal distending toxinlipopolysaccharidescytokine binding factorshorizontal gene transfer
collection DOAJ
language English
format Article
sources DOAJ
author Jan Oscarsson
Joseph DiRienzo
Anders Johansson
spellingShingle Jan Oscarsson
Joseph DiRienzo
Anders Johansson
Editorial Comments to the Special Issue: “<i>Aggregaterbacter actinomycetemcomitans</i>—Gram-Negative Bacterial Pathogen”
Pathogens
Aggregatibacter actinomycetemcomitans
leukotoxin
cytolethal distending toxin
lipopolysaccharides
cytokine binding factors
horizontal gene transfer
author_facet Jan Oscarsson
Joseph DiRienzo
Anders Johansson
author_sort Jan Oscarsson
title Editorial Comments to the Special Issue: “<i>Aggregaterbacter actinomycetemcomitans</i>—Gram-Negative Bacterial Pathogen”
title_short Editorial Comments to the Special Issue: “<i>Aggregaterbacter actinomycetemcomitans</i>—Gram-Negative Bacterial Pathogen”
title_full Editorial Comments to the Special Issue: “<i>Aggregaterbacter actinomycetemcomitans</i>—Gram-Negative Bacterial Pathogen”
title_fullStr Editorial Comments to the Special Issue: “<i>Aggregaterbacter actinomycetemcomitans</i>—Gram-Negative Bacterial Pathogen”
title_full_unstemmed Editorial Comments to the Special Issue: “<i>Aggregaterbacter actinomycetemcomitans</i>—Gram-Negative Bacterial Pathogen”
title_sort editorial comments to the special issue: “<i>aggregaterbacter actinomycetemcomitans</i>—gram-negative bacterial pathogen”
publisher MDPI AG
series Pathogens
issn 2076-0817
publishDate 2020-06-01
description <i>Aggregatibacter actinomycetemcomitans</i> is a periodontal pathogen colonizing the oral cavity in many individuals of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade the host inflammatory response. Both harmless and highly virulent genotypes of the bacterium have emerged because of the large genetic diversity within the species. The oral condition and age, as well as the geographic origin of the individual, influence the risk to be colonized by a virulent genotype of the bacterium. In the present editorial, the different genetic and virulence properties of <i>A. actinomycetemcomitans</i> will be addressed in relation to the publications in this Special Issue.
topic Aggregatibacter actinomycetemcomitans
leukotoxin
cytolethal distending toxin
lipopolysaccharides
cytokine binding factors
horizontal gene transfer
url https://www.mdpi.com/2076-0817/9/6/441
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AT andersjohansson editorialcommentstothespecialissueiaggregaterbacteractinomycetemcomitansigramnegativebacterialpathogen
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