An Antibody Screen of a Plasmodium vivax Antigen Library Identifies Novel Merozoite Proteins Associated with Clinical Protection.
BACKGROUND:Elimination of Plasmodium vivax malaria would be greatly facilitated by the development of an effective vaccine. A comprehensive and systematic characterization of antibodies to P. vivax antigens in exposed populations is useful in guiding rational vaccine design. METHODOLOGY/PRINCIPAL FI...
Main Authors: | Camila T França, Jessica B Hostetler, Sumana Sharma, Michael T White, Enmoore Lin, Benson Kiniboro, Andreea Waltmann, Andrew W Darcy, Connie S N Li Wai Suen, Peter Siba, Christopher L King, Julian C Rayner, Rick M Fairhurst, Ivo Mueller |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-05-01
|
Series: | PLoS Neglected Tropical Diseases |
Online Access: | http://europepmc.org/articles/PMC4868274?pdf=render |
Similar Items
-
IgG antibodies to synthetic GPI are biomarkers of immune-status to both Plasmodium falciparum and Plasmodium vivax malaria in young children
by: Camila T. França, et al.
Published: (2017-09-01) -
A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions.
by: Jessica B Hostetler, et al.
Published: (2015-12-01) -
Naturally acquired immune responses to P. vivax merozoite surface protein 3α and merozoite surface protein 9 are associated with reduced risk of P. vivax malaria in young Papua New Guinean children.
by: Danielle I Stanisic, et al.
Published: (2013-11-01) -
Plasmodium vivax Reticulocyte Binding Proteins Are Key Targets of Naturally Acquired Immunity in Young Papua New Guinean Children.
by: Camila T França, et al.
Published: (2016-09-01) -
A high force of plasmodium vivax blood-stage infection drives the rapid acquisition of immunity in papua new guinean children.
by: Cristian Koepfli, et al.
Published: (2013-01-01)