Leukocyte Mitochondrial DNA Copy Number Is Associated with Chronic Obstructive Pulmonary Disease.

BACKGROUND:Oxidative stress is known to be involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Evidence suggests that leukocytes mitochondria DNA (mtDNA) is susceptible to undergo mutations, insertions, or depletion in response to reactive oxidative stress (ROS). We hypothe...

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Bibliographic Details
Main Authors: Shih-Feng Liu, Ho-Chang Kuo, Ching-Wan Tseng, Hung-Tu Huang, Yung-Che Chen, Chia-Cheng Tseng, Meng-Chih Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4578933?pdf=render

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