Reactivation of M. tuberculosis infection in trans-membrane tumour necrosis factor mice.

Reactivation of M. tuberculosis infection in trans-membrane tumour necrosis factor mice.

Of those individuals who are infected with M. tuberculosis, 90% do not develop active disease and represents a large reservoir of M. tuberculosis with the potential for reactivation of infection. Sustained TNF expression is required for containment of persistent infection and TNF neutralization lead...

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Bibliographic Details
Main Authors: Ivy Dambuza, Roanne Keeton, Nasiema Allie, Nai-Jen Hsu, Philippa Randall, Boipelo Sebesho, Lizette Fick, Valerie J F Quesniaux, Muazzam Jacobs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3221652?pdf=render

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http://europepmc.org/articles/PMC3221652?pdf=render

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