Reactivation of M. tuberculosis infection in trans-membrane tumour necrosis factor mice.
Of those individuals who are infected with M. tuberculosis, 90% do not develop active disease and represents a large reservoir of M. tuberculosis with the potential for reactivation of infection. Sustained TNF expression is required for containment of persistent infection and TNF neutralization lead...
Main Authors: | Ivy Dambuza, Roanne Keeton, Nasiema Allie, Nai-Jen Hsu, Philippa Randall, Boipelo Sebesho, Lizette Fick, Valerie J F Quesniaux, Muazzam Jacobs |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3221652?pdf=render |
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