Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous system only in insulin-sensitive mice
Insulin signaling in the central nervous system (CNS) is required for the inhibitory effect of insulin on glucose production. Our aim was to determine whether the CNS is also involved in the stimulatory effect of circulating insulin on the tissue-specific retention of fatty acid (FA) from plasma. In...
Main Authors: | Claudia P. Coomans, Janine J. Geerling, Bruno Guigas, Anita M. van den Hoek, Edwin T. Parlevliet, D. Margriet Ouwens, Hanno Pijl, Peter J. Voshol, Patrick C.N. Rensen, Louis M. Havekes, Johannes A. Romijn |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2011-09-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520408624 |
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