Research Progress of Long Non-coding RNA in Esophageal Cancer

With the technological innovation of molecular biology research and the vigorous development of computer bioinformatics, the role of long non-coding RNA(lncRNA) and its biological functions have been studied intensively.It plays important roles in regulating the processes of cell cycle, growth and a...

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Bibliographic Details
Main Authors: CHEN Mengxue, LI Xueliang
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2018-11-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2018.18.0399.htm
Description
Summary:With the technological innovation of molecular biology research and the vigorous development of computer bioinformatics, the role of long non-coding RNA(lncRNA) and its biological functions have been studied intensively.It plays important roles in regulating the processes of cell cycle, growth and apoptosis.The abnormal expression of lncRNA is also closely related to the proliferation, migration and invasion of cancer.This review summarizes the research progress of lncRNAs and their regulatory mechanisms that influence the biological functions of esophageal cancer in recent two years, especially the role of lncRNA as a competitive endogenous RNA(ceRNA), so as to provide new ideas for the diagnosis and treatment of esophageal cancer.
ISSN:1000-8578
1000-8578