Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission.

Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission.

Vaginal HIV transmission accounts for the majority of new infections worldwide. Currently, multiple efforts to prevent HIV transmission are based on pre-exposure prophylaxis with various antiretroviral drugs. Here, we describe two novel nanoformulations of the reverse transcriptase inhibitor rilpivi...

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Bibliographic Details
Main Authors: Martina Kovarova, Olivia D Council, Abhijit A Date, Julie M Long, Tomonori Nochi, Michael Belshan, Annemarie Shibata, Heather Vincent, Caroline E Baker, William O Thayer, Guenter Kraus, Sophie Lachaud-Durand, Peter Williams, Christopher J Destache, J Victor Garcia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005075

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