<i>Apium</i> Plants: Beyond Simple Food and Phytopharmacological Applications

<i>Apium</i> plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical ben...

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Main Authors: Bahare Salehi, Alessandro Venditti, Claudio Frezza, Aysun Yücetepe, Ümit Altuntaş, Sibel Uluata, Monica Butnariu, Ioan Sarac, Shabnum Shaheen, Spyridon A. Petropoulos, Karl R. Matthews, Ceyda Sibel Kılıç, Maria Atanassova, Charles Oluwaseun Adetunji, Adedayo Oluwaseun Ademiluyi, Beraat Özçelik, Patrick Valere Tsouh Fokou, Natália Martins, William C. Cho, Javad Sharifi-Rad
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/9/17/3547
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language English
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author Bahare Salehi
Alessandro Venditti
Claudio Frezza
Aysun Yücetepe
Ümit Altuntaş
Sibel Uluata
Monica Butnariu
Ioan Sarac
Shabnum Shaheen
Spyridon A. Petropoulos
Karl R. Matthews
Ceyda Sibel Kılıç
Maria Atanassova
Charles Oluwaseun Adetunji
Adedayo Oluwaseun Ademiluyi
Beraat Özçelik
Patrick Valere Tsouh Fokou
Natália Martins
William C. Cho
Javad Sharifi-Rad
spellingShingle Bahare Salehi
Alessandro Venditti
Claudio Frezza
Aysun Yücetepe
Ümit Altuntaş
Sibel Uluata
Monica Butnariu
Ioan Sarac
Shabnum Shaheen
Spyridon A. Petropoulos
Karl R. Matthews
Ceyda Sibel Kılıç
Maria Atanassova
Charles Oluwaseun Adetunji
Adedayo Oluwaseun Ademiluyi
Beraat Özçelik
Patrick Valere Tsouh Fokou
Natália Martins
William C. Cho
Javad Sharifi-Rad
<i>Apium</i> Plants: Beyond Simple Food and Phytopharmacological Applications
Applied Sciences
<i>Apium</i>
botany
medicinal use
phytochemicals
pharmacological properties
author_facet Bahare Salehi
Alessandro Venditti
Claudio Frezza
Aysun Yücetepe
Ümit Altuntaş
Sibel Uluata
Monica Butnariu
Ioan Sarac
Shabnum Shaheen
Spyridon A. Petropoulos
Karl R. Matthews
Ceyda Sibel Kılıç
Maria Atanassova
Charles Oluwaseun Adetunji
Adedayo Oluwaseun Ademiluyi
Beraat Özçelik
Patrick Valere Tsouh Fokou
Natália Martins
William C. Cho
Javad Sharifi-Rad
author_sort Bahare Salehi
title <i>Apium</i> Plants: Beyond Simple Food and Phytopharmacological Applications
title_short <i>Apium</i> Plants: Beyond Simple Food and Phytopharmacological Applications
title_full <i>Apium</i> Plants: Beyond Simple Food and Phytopharmacological Applications
title_fullStr <i>Apium</i> Plants: Beyond Simple Food and Phytopharmacological Applications
title_full_unstemmed <i>Apium</i> Plants: Beyond Simple Food and Phytopharmacological Applications
title_sort <i>apium</i> plants: beyond simple food and phytopharmacological applications
publisher MDPI AG
series Applied Sciences
issn 2076-3417
publishDate 2019-08-01
description <i>Apium</i> plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of <i>Apium</i> plants and provides future direction on how to take full advantage of <i>Apium</i> plants for the optimal benefit to mankind.
topic <i>Apium</i>
botany
medicinal use
phytochemicals
pharmacological properties
url https://www.mdpi.com/2076-3417/9/17/3547
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spelling doaj-e2bad3090649412d8138da7bee8726252020-11-25T02:45:29ZengMDPI AGApplied Sciences2076-34172019-08-01917354710.3390/app9173547app9173547<i>Apium</i> Plants: Beyond Simple Food and Phytopharmacological ApplicationsBahare Salehi0Alessandro Venditti1Claudio Frezza2Aysun Yücetepe3Ümit Altuntaş4Sibel Uluata5Monica Butnariu6Ioan Sarac7Shabnum Shaheen8Spyridon A. Petropoulos9Karl R. Matthews10Ceyda Sibel Kılıç11Maria Atanassova12Charles Oluwaseun Adetunji13Adedayo Oluwaseun Ademiluyi14Beraat Özçelik15Patrick Valere Tsouh Fokou16Natália Martins17William C. Cho18Javad Sharifi-Rad19Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, IranDipartimento di Chimica, Università di Roma “La Sapienza”, Piazzale Aldo Moro 5, 00185 Rome, ItalyDipartimento di Biologia Ambientale, Università di Roma “La Sapienza”, Piazzale Aldo Moro 5, 00185 Rome, ItalyDepartment of Food Engineering, Faculty of Engineering, Aksaray University, Aksaray 68100, TurkeyDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Maslak, Istanbul 34469, TurkeyDepartment of Food Technology, Inonu University, Malatya 44280, TurkeyChemistry &amp; Biochemistry Discipline, Banat’s University of Agricultural Sciences and Veterinary Medicine “King Michael I of Romania” from Timisoara, 300645, Calea Aradului 119, Timis, RomaniaChemistry &amp; Biochemistry Discipline, Banat’s University of Agricultural Sciences and Veterinary Medicine “King Michael I of Romania” from Timisoara, 300645, Calea Aradului 119, Timis, RomaniaChemotaxonomic Lab., Lahore College for Women University, Lahore 54000, PakistanLaboratory of Vegetable Production, University of Thessaly, Fytokou Street, 38446 N. Ionia, Magnissia, GreeceDepartment of Food Science, Rutgers University, New Brunswick, NJ 08901, USADepartment of Pharmaceutical Botany, Faculty of Pharmacy, Ankara University, Ankara 06100, TurkeyScientific Consulting, Chemical Engineering, UCTM, P.O. Box 1756 Sofia, BulgariaApplied Microbiology, Biotechnology and Nanotechnology Laboratory, Department of Microbiology, Edo University, Iyamho, Edo State 300271, NigeriaFunctional Foods, Nutraceuticals and Phytomedicine Unit, Department of Biochemistry, Federal University of Technology, Akure 340001, NigeriaDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Maslak, Istanbul 34469, TurkeyAntimicrobial and Biocontrol Agents Unit, Department of Biochemistry, Faculty of Science, University of Yaounde 1, Ngoa Ekelle, Annex Fac. Sci, P.O. Box. 812, Yaounde, CameroonFaculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, PortugalDepartment of Clinical Oncology, Queen Elizabeth Hospital, 30 Gascoigne Road, Hong Kong, ChinaZabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol 61615-585, Iran<i>Apium</i> plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of <i>Apium</i> plants and provides future direction on how to take full advantage of <i>Apium</i> plants for the optimal benefit to mankind.https://www.mdpi.com/2076-3417/9/17/3547<i>Apium</i>botanymedicinal usephytochemicalspharmacological properties