Eco-friendly synthesis of AuNPs for cutaneous wound-healing applications in nursing care after surgery

• Main Authors: Nie Shijun, Wei Ran, Zhou Haoxin, Zhang Liang, Chen Zhinan, Hou Limin
• Format: Article
• Language: English
• Published: De Gruyter 2020-07-01
• Series: Green Processing and Synthesis
• Subjects: aunps; polyphenols; wound healing; care
• Online Access: https://doi.org/10.1515/gps-2020-0037

The current work described the preparation of gold nanoparticles (AuNPs) using the plant extract of Impatiens balsamina followed by evaluating their wound-healing potential. The formed NPs were studied by performing UV-visible spectroscopy, Fourier transform infrared, transmission electron microscopy and X-ray diffraction. Further, both the thermal and excision wound models were used to understand the wound-healing ability of AuNPs. It is exhibited that at a concentration of 20 mg, the AuNPs exhibited substantial decrease in excision wound within 8 days. The obtained wound-healing results indicated that the AuNPs prepared from the leaf extract of I. balsamina exhibited active wound-healing potential when related to traditional drugs; hence, AuNPs could have future applications in the development of dressing materials in nursing care for wound healing after surgery.