Does Probiotic Yeast Act as Antigenotoxin?

The effect of probiotic yeast Saccharomyces boulardii on genotoxicity induced by the well-known mutagen 4-nitroquinoline-N-oxide (4-NQO), as well as antibacterial (furazolidone) and antibiotic (nalidixic acid) drugs, has been studied using the short-term bacterial assay, SOS chromotest, with Escheri...

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Bibliographic Details
Main Authors: Jekabs Raipulis, Inta Kalnina, Reinis Rutkis, Malda Maija Toma
Format: Article
Language:English
Published: University of Zagreb 2005-01-01
Series:Food Technology and Biotechnology
Subjects:
Online Access:http://hrcak.srce.hr/file/162908
Description
Summary:The effect of probiotic yeast Saccharomyces boulardii on genotoxicity induced by the well-known mutagen 4-nitroquinoline-N-oxide (4-NQO), as well as antibacterial (furazolidone) and antibiotic (nalidixic acid) drugs, has been studied using the short-term bacterial assay, SOS chromotest, with Escherichia coli PQ 37 as the test organism. It has been shown that S. boulardii possesses antigenotoxic activity, revealed by SOS chromotest, when coincubated with these genotoxins. A weaker antigenotoxic activity against the same compounds was observed with S. carlsbergensis, too.
ISSN:1330-9862
1334-2606