MicroRNA93 regulates proliferation and differentiation of normal and malignant breast stem cells.

MicroRNA93 regulates proliferation and differentiation of normal and malignant breast stem cells.

MicroRNAs (miRNAs) play important roles in normal cellular differentiation and oncogenesis. microRNA93 (mir-93), a member of the mir106b-25 cluster, located in intron 13 of the MCM7 gene, although frequently overexpressed in human malignancies may also function as a tumor suppressor gene. Using a se...

Full description

Bibliographic Details
Main Authors: Suling Liu, Shivani H Patel, Christophe Ginestier, Ingrid Ibarra, Rachel Martin-Trevino, Shoumin Bai, Sean P McDermott, Li Shang, Jia Ke, Sing J Ou, Amber Heath, Kevin J Zhang, Hasan Korkaya, Shawn G Clouthier, Emmanuelle Charafe-Jauffret, Daniel Birnbaum, Gregory J Hannon, Max S Wicha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3369932?pdf=render

Internet

http://europepmc.org/articles/PMC3369932?pdf=render

Similar Items