Diabetic neuropathy
ABSTRACT BACKGROUND AND OBJECTIVES: Diabetic neuropathy is a major cause of neuropathy worldwide and may lead to amputations and incapacity. This study aimed at a detailed and updated review on diabetic neuropathy, focusing on its classification, diagnostic investigation and treatment. CONTENTS: I...
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doaj-e2e64ecda0884f939248d8ae3cdf5f632020-11-25T03:37:49ZengSociedade Brasileira para o Estudo da DorRevista Dor1806-00132317-639317suppl 1465110.5935/1806-0013.20160047S1806-00132016000500046Diabetic neuropathyOsvaldo José Moreira do NascimentoCamila Castelo Branco PupeEduardo Boiteux Uchôa CavalcantiABSTRACT BACKGROUND AND OBJECTIVES: Diabetic neuropathy is a major cause of neuropathy worldwide and may lead to amputations and incapacity. This study aimed at a detailed and updated review on diabetic neuropathy, focusing on its classification, diagnostic investigation and treatment. CONTENTS: It is estimated that 371 million people aged from 20 to 79 years, worldwide, have diabetes mellitus and that at least half of them are unware of the diagnosis. Its prevalence in Central and South America was estimated in 26.4 million people, corresponding to approximately 6.5% of the population. Among microvascular complications, diabetic neuropathy is the most prevalent, leading to the highest rates of hospitalization, atraumatic amputations and incapacity. Diabetic neuropathy may have different clinical presentations, being distal symmetric polyneuropathy its most frequent presentation and major mechanism to the development of diabetic foot. Predominantly it presents with positive (burning, tingling) and negative (numbness, loss of sensitivity) sensory symptoms. In general it is associated to autonomic signs and symptoms and seldom there is motor manifestation. Approximately 20% of patients with distal symmetric polyneuropathy have neuropathic pain, which sometimes becomes chronic and disabling. CONCLUSION: Early and accurate diagnosis allows for adequate treatment, preventing progression of neuropathy and severe complications. For such, it is necessary to obtain an acurate clinical history, in addition to thorough neurological tests and additional tests, to identify signs of nervous fibers involvement. Its treatment depends on adequate glycemic control and neuropathic pain treatment, when present.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132016000500046&lng=en&tlng=endiabetes mellitusdor neuropáticaneuropatia diabéticaneuropatia periférica |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Osvaldo José Moreira do Nascimento Camila Castelo Branco Pupe Eduardo Boiteux Uchôa Cavalcanti |
spellingShingle |
Osvaldo José Moreira do Nascimento Camila Castelo Branco Pupe Eduardo Boiteux Uchôa Cavalcanti Diabetic neuropathy Revista Dor diabetes mellitus dor neuropática neuropatia diabética neuropatia periférica |
author_facet |
Osvaldo José Moreira do Nascimento Camila Castelo Branco Pupe Eduardo Boiteux Uchôa Cavalcanti |
author_sort |
Osvaldo José Moreira do Nascimento |
title |
Diabetic neuropathy |
title_short |
Diabetic neuropathy |
title_full |
Diabetic neuropathy |
title_fullStr |
Diabetic neuropathy |
title_full_unstemmed |
Diabetic neuropathy |
title_sort |
diabetic neuropathy |
publisher |
Sociedade Brasileira para o Estudo da Dor |
series |
Revista Dor |
issn |
1806-0013 2317-6393 |
description |
ABSTRACT BACKGROUND AND OBJECTIVES: Diabetic neuropathy is a major cause of neuropathy worldwide and may lead to amputations and incapacity. This study aimed at a detailed and updated review on diabetic neuropathy, focusing on its classification, diagnostic investigation and treatment. CONTENTS: It is estimated that 371 million people aged from 20 to 79 years, worldwide, have diabetes mellitus and that at least half of them are unware of the diagnosis. Its prevalence in Central and South America was estimated in 26.4 million people, corresponding to approximately 6.5% of the population. Among microvascular complications, diabetic neuropathy is the most prevalent, leading to the highest rates of hospitalization, atraumatic amputations and incapacity. Diabetic neuropathy may have different clinical presentations, being distal symmetric polyneuropathy its most frequent presentation and major mechanism to the development of diabetic foot. Predominantly it presents with positive (burning, tingling) and negative (numbness, loss of sensitivity) sensory symptoms. In general it is associated to autonomic signs and symptoms and seldom there is motor manifestation. Approximately 20% of patients with distal symmetric polyneuropathy have neuropathic pain, which sometimes becomes chronic and disabling. CONCLUSION: Early and accurate diagnosis allows for adequate treatment, preventing progression of neuropathy and severe complications. For such, it is necessary to obtain an acurate clinical history, in addition to thorough neurological tests and additional tests, to identify signs of nervous fibers involvement. Its treatment depends on adequate glycemic control and neuropathic pain treatment, when present. |
topic |
diabetes mellitus dor neuropática neuropatia diabética neuropatia periférica |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132016000500046&lng=en&tlng=en |
work_keys_str_mv |
AT osvaldojosemoreiradonascimento diabeticneuropathy AT camilacastelobrancopupe diabeticneuropathy AT eduardoboiteuxuchoacavalcanti diabeticneuropathy |
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