Acupuncture for Depression: A Systematic Review and Meta-Analysis
Background: Depression is commonly treated with anti-depressant medication and/or psychological interventions. Patients with depression are common users of complementary therapies, such as acupuncture, either as a replacement for, or adjunct to, their conventional treatments. This systematic review...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-07-01
|
Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0383/8/8/1140 |
id |
doaj-e2ea8971855440b5a4683ec4b574e630 |
---|---|
record_format |
Article |
spelling |
doaj-e2ea8971855440b5a4683ec4b574e6302020-11-24T21:34:29ZengMDPI AGJournal of Clinical Medicine2077-03832019-07-0188114010.3390/jcm8081140jcm8081140Acupuncture for Depression: A Systematic Review and Meta-AnalysisMike Armour0Caroline A. Smith1Li-Qiong Wang2Dhevaksha Naidoo3Guo-Yan Yang4Hugh MacPherson5Myeong Soo Lee6Phillipa Hay7NICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, AustraliaNICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, AustraliaSchool of Acupuncture and Moxibustion, Beijing University of Chinese Medicine, Beijing 100029, ChinaNICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, AustraliaNICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, AustraliaDepartment of Health Sciences, University of York, Heslington, York YO10 5DD, UKClinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, KoreaTranslational Health Research Institute, School of Medicine, Western Sydney University, Penrith, NSW 2751, AustraliaBackground: Depression is commonly treated with anti-depressant medication and/or psychological interventions. Patients with depression are common users of complementary therapies, such as acupuncture, either as a replacement for, or adjunct to, their conventional treatments. This systematic review and meta-analysis examined the effectiveness of acupuncture in major depressive disorder. Methods: A search of English (Medline, PsychINFO, Google Scholar, and CINAL), Chinese (China National Knowledge Infrastructure Database (CNKI) and Wanfang Database), and Korean databases was undertaken from 1980 to November 2018 for clinical trials using manual, electro, or laser acupuncture. Results: Twenty-nine studies including 2268 participants were eligible and included in the meta-analysis. Twenty-two trials were undertaken in China and seven outside of China. Acupuncture showed clinically significant reductions in the severity of depression compared to usual care (Hedges (g) = 0.41, 95% confidence interval (CI) 0.18 to 0.63), sham acupuncture (g = 0.55, 95% CI 0.31 to 0.79), and as an adjunct to anti-depressant medication (g = 0.84, 95% CI 0.61 to 1.07). A significant correlation between an increase in the number of acupuncture treatments delivered and reduction in the severity of depression (<i>p</i> = 0.015) was found. Limitations: The majority of the included trials were at a high risk of bias for performance blinding. The applicability of findings in Chinese populations to other populations is unclear, due to the use of a higher treatment frequency and number of treatments in China. The majority of trials did not report any post-trial follow-up and safety reporting was poor. Conclusions: Acupuncture may be a suitable adjunct to usual care and standard anti-depressant medication.https://www.mdpi.com/2077-0383/8/8/1140depressionacupuncturedosagefrequency |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mike Armour Caroline A. Smith Li-Qiong Wang Dhevaksha Naidoo Guo-Yan Yang Hugh MacPherson Myeong Soo Lee Phillipa Hay |
spellingShingle |
Mike Armour Caroline A. Smith Li-Qiong Wang Dhevaksha Naidoo Guo-Yan Yang Hugh MacPherson Myeong Soo Lee Phillipa Hay Acupuncture for Depression: A Systematic Review and Meta-Analysis Journal of Clinical Medicine depression acupuncture dosage frequency |
author_facet |
Mike Armour Caroline A. Smith Li-Qiong Wang Dhevaksha Naidoo Guo-Yan Yang Hugh MacPherson Myeong Soo Lee Phillipa Hay |
author_sort |
Mike Armour |
title |
Acupuncture for Depression: A Systematic Review and Meta-Analysis |
title_short |
Acupuncture for Depression: A Systematic Review and Meta-Analysis |
title_full |
Acupuncture for Depression: A Systematic Review and Meta-Analysis |
title_fullStr |
Acupuncture for Depression: A Systematic Review and Meta-Analysis |
title_full_unstemmed |
Acupuncture for Depression: A Systematic Review and Meta-Analysis |
title_sort |
acupuncture for depression: a systematic review and meta-analysis |
publisher |
MDPI AG |
series |
Journal of Clinical Medicine |
issn |
2077-0383 |
publishDate |
2019-07-01 |
description |
Background: Depression is commonly treated with anti-depressant medication and/or psychological interventions. Patients with depression are common users of complementary therapies, such as acupuncture, either as a replacement for, or adjunct to, their conventional treatments. This systematic review and meta-analysis examined the effectiveness of acupuncture in major depressive disorder. Methods: A search of English (Medline, PsychINFO, Google Scholar, and CINAL), Chinese (China National Knowledge Infrastructure Database (CNKI) and Wanfang Database), and Korean databases was undertaken from 1980 to November 2018 for clinical trials using manual, electro, or laser acupuncture. Results: Twenty-nine studies including 2268 participants were eligible and included in the meta-analysis. Twenty-two trials were undertaken in China and seven outside of China. Acupuncture showed clinically significant reductions in the severity of depression compared to usual care (Hedges (g) = 0.41, 95% confidence interval (CI) 0.18 to 0.63), sham acupuncture (g = 0.55, 95% CI 0.31 to 0.79), and as an adjunct to anti-depressant medication (g = 0.84, 95% CI 0.61 to 1.07). A significant correlation between an increase in the number of acupuncture treatments delivered and reduction in the severity of depression (<i>p</i> = 0.015) was found. Limitations: The majority of the included trials were at a high risk of bias for performance blinding. The applicability of findings in Chinese populations to other populations is unclear, due to the use of a higher treatment frequency and number of treatments in China. The majority of trials did not report any post-trial follow-up and safety reporting was poor. Conclusions: Acupuncture may be a suitable adjunct to usual care and standard anti-depressant medication. |
topic |
depression acupuncture dosage frequency |
url |
https://www.mdpi.com/2077-0383/8/8/1140 |
work_keys_str_mv |
AT mikearmour acupuncturefordepressionasystematicreviewandmetaanalysis AT carolineasmith acupuncturefordepressionasystematicreviewandmetaanalysis AT liqiongwang acupuncturefordepressionasystematicreviewandmetaanalysis AT dhevakshanaidoo acupuncturefordepressionasystematicreviewandmetaanalysis AT guoyanyang acupuncturefordepressionasystematicreviewandmetaanalysis AT hughmacpherson acupuncturefordepressionasystematicreviewandmetaanalysis AT myeongsoolee acupuncturefordepressionasystematicreviewandmetaanalysis AT phillipahay acupuncturefordepressionasystematicreviewandmetaanalysis |
_version_ |
1725949172892303360 |