Triethylenetetramine Synergizes with Pharmacologic Ascorbic Acid in Hydrogen Peroxide Mediated Selective Toxicity to Breast Cancer Cell
Breast cancer is characterized by overexpression of superoxide dismutase (SOD) and downregulation of catalase and more resistance to hydrogen peroxide (H2O2) than normal cells. Thus, relatively high H2O2 promotes breast cancer cell growth and proliferation. However, excessive intracellular H2O2 lead...
Main Authors: | Lianlian Wang, Xiaofang Luo, Cong Li, Yubing Huang, Ping Xu, Laetitia H. Lloyd-Davies, Thibaut Delplancke, Chuan Peng, Rufei Gao, Hongbo Qi, Chao Tong, Philip Baker |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
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Series: | Oxidative Medicine and Cellular Longevity |
Online Access: | http://dx.doi.org/10.1155/2017/3481710 |
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