Mucosal Involvement in Bullous Pemphigoid Is Mostly Associated with Disease Severity and to Absence of Anti-BP230 Autoantibody

Mucosal Involvement in Bullous Pemphigoid Is Mostly Associated with Disease Severity and to Absence of Anti-BP230 Autoantibody

Bullous pemphigoid (BP) is the most common autoimmune bullous disease and typically affects the elderly. Binding of specific autoantibodies to BP180/230 hemidesmosomal components induces an inflammatory response leading to skin blister formation. Unusual manifestations of BP include additional mucou...

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Bibliographic Details
Main Authors: Ariane Clapé, Céline Muller, Grégory Gatouillat, Sébastien Le Jan, Coralie Barbe, Bach-Nga Pham, Frank Antonicelli, Philippe Bernard
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
bullous pemphigoid
BP Disease Area Index
mucosal involvement
anti-BP230
autoantibodies
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00479/full

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