TLR2 and Dectin-1 Signaling in Mouse Hematopoietic Stem and Progenitor Cells Impacts the Ability of the Antigen Presenting Cells They Produce to Activate CD4 T Cells
Microbial recognition by pattern recognition receptors (PRRs) expressed on hematopoietic stem and progenitor cells (HSPCs) not only activates myelopoiesis but also programs the function of the monocytes and macrophages they produce. For instance, changes in HSPC programming modify the ability of mac...
Main Authors: | Alba Martínez, Cristina Bono, Daniel Gozalbo, Helen S. Goodridge, M. Luisa Gil, Alberto Yáñez |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-05-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/5/1317 |
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