Development of an mRNA-LNP Vaccine against SARS-CoV-2: Evaluation of Immune Response in Mouse and Rhesus Macaque

Development of an mRNA-LNP Vaccine against SARS-CoV-2: Evaluation of Immune Response in Mouse and Rhesus Macaque

Among the vaccines have been developed thus far against SARS-CoV-2, the mRNA-based ones have demonstrated more promising results regarding both safety and efficacy. Two remarkable features of the mRNA vaccines introduced by the Pfizer/BioNTech and Moderna companies are the use of (N<sup>1</...

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Bibliographic Details
Main Authors: Alireza Naderi Sohi, Jafar Kiani, Ehsan Arefian, Arezou Khosrojerdi, Zahra Fekrirad, Shokoofeh Ghaemi, Mohammad Kazem Zim, Arsalan Jalili, Nazila Bostanshirin, Masoud Soleimani
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Vaccines
Subjects:
mRNA-vaccine
lipid nanoparticle
LNP
SARS-CoV-2
spike protein
Online Access:https://www.mdpi.com/2076-393X/9/9/1007

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