Translation of the circular RNA circβ-catenin promotes liver cancer cell growth through activation of the Wnt pathway

Translation of the circular RNA circβ-catenin promotes liver cancer cell growth through activation of the Wnt pathway

Abstract Background Circular RNAs are a class of regulatory RNA transcripts, which are ubiquitously expressed in eukaryotes. In the current study, we evaluate the function of a novel circRNA derived from the β-catenin gene locus, circβ-catenin. Results Circβ-catenin is predominantly localized in the...

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Bibliographic Details
Main Authors: Wei-Cheng Liang, Cheuk-Wa Wong, Pu-Ping Liang, Mai Shi, Ye Cao, Shi-Tao Rao, Stephen Kwok-Wing Tsui, Mary Miu-Yee Waye, Qi Zhang, Wei-Ming Fu, Jin-Fang Zhang
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Genome Biology
Subjects:
Circular RNA
Non-coding RNA
Coding capacity
Wnt pathway
Cell growth
Online Access:http://link.springer.com/article/10.1186/s13059-019-1685-4

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