Suppression of superoxide anion and elastase release by C18 unsaturated fatty acids in human neutrophils

Suppression of superoxide anion and elastase release by C18 unsaturated fatty acids in human neutrophils

The structure-activity relationship of 18-carbon fatty acids (C18 FAs) on human neutrophil functions and their underlying mechanism were investigated. C18 unsaturated (U)FAs potently inhibited superoxide anion production, elastase release, and Ca2+ mobilization at concentrations of <10 μM in form...

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Bibliographic Details
Main Authors:	Tsong-Long Hwang, Yi-Chia Su, Han-Lin Chang, Yann-Lii Leu, Pei-Jen Chung, Liang-Mou Kuo, Yi-Ju Chang
Format:	Article
Language:	English
Published:	Elsevier 2009-07-01
Series:	Journal of Lipid Research
Subjects:	calcium cAMP structure-activity relationship plasma membrane Ca2+-ATPase
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520307872

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