Comparison of MLPA Method for Detection of Known and Unknown Deletions in Beta Globin Gene Cluster with Old Methods (REAL-TIME, RFLP, Gap-PCR)

Comparison of MLPA Method for Detection of Known and Unknown Deletions in Beta Globin Gene Cluster with Old Methods (REAL-TIME, RFLP, Gap-PCR)

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Background and ObjectivesThalassaemia is one of the most common single gene disorders, which is most prevalent in the Mediterranean, the Middle East, Indian subcontinent (malaria belt). One of the mutations that result in Thalassaemia is the deletion in beta globin gene cluster. These deletions caus...

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Bibliographic Details
Main Authors: R. Alimohammadi, M. Raiesi, A. Ebrahimi, S. Fallah, S. Kianfar, M. Masoudifar, S. Jamali, S. Babashah, M. Karimipour, R. Mahdian, S. Zeinali
Format: Article
Language:fas
Published: Qom University of Medical Sciences 2009-02-01
Series:Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Subjects:
Bata-Globins
Beta-Globins-Genetics
Thalassemia-Genetics.
Online Access:http://journal.muq.ac.ir/library/upload/article/87.8.1.pdf

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