Microfluidic Systems Applied in Solid-State Nanopore Sensors
Microfluidic system, as a kind of miniature integrated operating platform, has been applied to solid-state nanopore sensors after many years of experimental study. In the process of introducing microfluidic into solid-state nanopore sensors, many novel device structures are designed due to the abund...
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MDPI AG
2020-03-01
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| Series: | Micromachines |
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| Online Access: | https://www.mdpi.com/2072-666X/11/3/332 |
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doaj-e33e54690b8c43be82a0f8a7ba93215d2020-11-25T02:10:43ZengMDPI AGMicromachines2072-666X2020-03-0111333210.3390/mi11030332mi11030332Microfluidic Systems Applied in Solid-State Nanopore SensorsJiye Fu0Linlin Wu1Yi Qiao2Jing Tu3Zuhong Lu4State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, ChinaState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, ChinaState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, ChinaState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, ChinaState Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, ChinaMicrofluidic system, as a kind of miniature integrated operating platform, has been applied to solid-state nanopore sensors after many years of experimental study. In the process of introducing microfluidic into solid-state nanopore sensors, many novel device structures are designed due to the abundance of analytes and the diversity of detection methods. Here we review the fundamental setup of nanopore-based microfluidic systems and the developments and advancements that have been taking place in the field. The microfluidic systems with a multichannel strategy to elevate the throughput and efficiency of nanopore sensors are then presented. Multifunctional detection represented by optical-electrical detection, which is realized by microfluidic integration, is also described. A high integration microfluidic system with nanopore is further discussed, which shows the prototype of commercialization.https://www.mdpi.com/2072-666X/11/3/332solid-state nanoporemicrofluidic systemmultichanneloptical detectionintegration |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Jiye Fu Linlin Wu Yi Qiao Jing Tu Zuhong Lu |
| spellingShingle |
Jiye Fu Linlin Wu Yi Qiao Jing Tu Zuhong Lu Microfluidic Systems Applied in Solid-State Nanopore Sensors Micromachines solid-state nanopore microfluidic system multichannel optical detection integration |
| author_facet |
Jiye Fu Linlin Wu Yi Qiao Jing Tu Zuhong Lu |
| author_sort |
Jiye Fu |
| title |
Microfluidic Systems Applied in Solid-State Nanopore Sensors |
| title_short |
Microfluidic Systems Applied in Solid-State Nanopore Sensors |
| title_full |
Microfluidic Systems Applied in Solid-State Nanopore Sensors |
| title_fullStr |
Microfluidic Systems Applied in Solid-State Nanopore Sensors |
| title_full_unstemmed |
Microfluidic Systems Applied in Solid-State Nanopore Sensors |
| title_sort |
microfluidic systems applied in solid-state nanopore sensors |
| publisher |
MDPI AG |
| series |
Micromachines |
| issn |
2072-666X |
| publishDate |
2020-03-01 |
| description |
Microfluidic system, as a kind of miniature integrated operating platform, has been applied to solid-state nanopore sensors after many years of experimental study. In the process of introducing microfluidic into solid-state nanopore sensors, many novel device structures are designed due to the abundance of analytes and the diversity of detection methods. Here we review the fundamental setup of nanopore-based microfluidic systems and the developments and advancements that have been taking place in the field. The microfluidic systems with a multichannel strategy to elevate the throughput and efficiency of nanopore sensors are then presented. Multifunctional detection represented by optical-electrical detection, which is realized by microfluidic integration, is also described. A high integration microfluidic system with nanopore is further discussed, which shows the prototype of commercialization. |
| topic |
solid-state nanopore microfluidic system multichannel optical detection integration |
| url |
https://www.mdpi.com/2072-666X/11/3/332 |
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