Quercitrin from Toona sinensis (Juss.) M.Roem. Attenuates Acetaminophen-Induced Acute Liver Toxicity in HepG2 Cells and Mice through Induction of Antioxidant Machinery and Inhibition of Inflammation

Quercitrin from Toona sinensis (Juss.) M.Roem. Attenuates Acetaminophen-Induced Acute Liver Toxicity in HepG2 Cells and Mice through Induction of Antioxidant Machinery and Inhibition of Inflammation

Quercitrin is found in many kinds of vegetables and fruits, and possesses various bioactive properties. The aim of the present study was to elucidate hepatoprotective mechanisms of quercitrin isolated from Toona sinensis (Juss.) M.Roem. (syn. Cedrela sinensis Juss.), using acetaminophen (APAP)-treat...

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Bibliographic Details
Main Authors: Van-Long Truong, Se-Yeon Ko, Mira Jun, Woo-Sik Jeong
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Nutrients
Subjects:
quercitrin
acetaminophen
hepatoprotection
Nrf2/ARE
antioxidant
Online Access:http://www.mdpi.com/2072-6643/8/7/431

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