Adenosquamous Carcinoma of the Choledochus
The patient was an 86-year-old man who was admitted with obstructive jaundice. Computed tomography revealed a tumor in the hilar choledochus with peripheral hepatic duct dilatation. Endoscopic cholangiography (ERC) demonstrated the defect in the choledochus. Brushing cytology during ERC showed Orang...
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doaj-e37a51b3a4f8407f9df559dfbff0d53a2020-11-24T21:50:10ZengKarger PublishersCase Reports in Gastroenterology1662-06312019-01-0112377377910.1159/000495936495936Adenosquamous Carcinoma of the CholedochusDaisuke UeharaHitoshi TakagiTakashi HoshinoYuhei SuzukiSatoshi TakakusagiKyoko MaruhashiKazuko KizawaTakashi KosoneAtsushi NaganumaEtsuko HisanagaJunko HiratoSatoru KakizakiToshio UraokaThe patient was an 86-year-old man who was admitted with obstructive jaundice. Computed tomography revealed a tumor in the hilar choledochus with peripheral hepatic duct dilatation. Endoscopic cholangiography (ERC) demonstrated the defect in the choledochus. Brushing cytology during ERC showed Orange-G-philic keratinized atypical cells, which led to a diagnosis of squamous cell carcinoma. Chemotherapy with tegafur-gimeracil-oteracil potassium was ineffective and was discontinued due to adverse effects. The patient died 5 months after the diagnosis and autopsy revealed tubular adenocarcinoma of the hilar bile duct with squamous cell carcinoma component. Progression of the disease might influence the distribution of adenosquamous carcinoma. The clinicopathological sequence of adenosquamous carcinoma of the choledochus was documented.https://www.karger.com/Article/FullText/495936Adenosquamous carcinomaCholedochus cancer |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Daisuke Uehara Hitoshi Takagi Takashi Hoshino Yuhei Suzuki Satoshi Takakusagi Kyoko Maruhashi Kazuko Kizawa Takashi Kosone Atsushi Naganuma Etsuko Hisanaga Junko Hirato Satoru Kakizaki Toshio Uraoka |
spellingShingle |
Daisuke Uehara Hitoshi Takagi Takashi Hoshino Yuhei Suzuki Satoshi Takakusagi Kyoko Maruhashi Kazuko Kizawa Takashi Kosone Atsushi Naganuma Etsuko Hisanaga Junko Hirato Satoru Kakizaki Toshio Uraoka Adenosquamous Carcinoma of the Choledochus Case Reports in Gastroenterology Adenosquamous carcinoma Choledochus cancer |
author_facet |
Daisuke Uehara Hitoshi Takagi Takashi Hoshino Yuhei Suzuki Satoshi Takakusagi Kyoko Maruhashi Kazuko Kizawa Takashi Kosone Atsushi Naganuma Etsuko Hisanaga Junko Hirato Satoru Kakizaki Toshio Uraoka |
author_sort |
Daisuke Uehara |
title |
Adenosquamous Carcinoma of the Choledochus |
title_short |
Adenosquamous Carcinoma of the Choledochus |
title_full |
Adenosquamous Carcinoma of the Choledochus |
title_fullStr |
Adenosquamous Carcinoma of the Choledochus |
title_full_unstemmed |
Adenosquamous Carcinoma of the Choledochus |
title_sort |
adenosquamous carcinoma of the choledochus |
publisher |
Karger Publishers |
series |
Case Reports in Gastroenterology |
issn |
1662-0631 |
publishDate |
2019-01-01 |
description |
The patient was an 86-year-old man who was admitted with obstructive jaundice. Computed tomography revealed a tumor in the hilar choledochus with peripheral hepatic duct dilatation. Endoscopic cholangiography (ERC) demonstrated the defect in the choledochus. Brushing cytology during ERC showed Orange-G-philic keratinized atypical cells, which led to a diagnosis of squamous cell carcinoma. Chemotherapy with tegafur-gimeracil-oteracil potassium was ineffective and was discontinued due to adverse effects. The patient died 5 months after the diagnosis and autopsy revealed tubular adenocarcinoma of the hilar bile duct with squamous cell carcinoma component. Progression of the disease might influence the distribution of adenosquamous carcinoma. The clinicopathological sequence of adenosquamous carcinoma of the choledochus was documented. |
topic |
Adenosquamous carcinoma Choledochus cancer |
url |
https://www.karger.com/Article/FullText/495936 |
work_keys_str_mv |
AT daisukeuehara adenosquamouscarcinomaofthecholedochus AT hitoshitakagi adenosquamouscarcinomaofthecholedochus AT takashihoshino adenosquamouscarcinomaofthecholedochus AT yuheisuzuki adenosquamouscarcinomaofthecholedochus AT satoshitakakusagi adenosquamouscarcinomaofthecholedochus AT kyokomaruhashi adenosquamouscarcinomaofthecholedochus AT kazukokizawa adenosquamouscarcinomaofthecholedochus AT takashikosone adenosquamouscarcinomaofthecholedochus AT atsushinaganuma adenosquamouscarcinomaofthecholedochus AT etsukohisanaga adenosquamouscarcinomaofthecholedochus AT junkohirato adenosquamouscarcinomaofthecholedochus AT satorukakizaki adenosquamouscarcinomaofthecholedochus AT toshiouraoka adenosquamouscarcinomaofthecholedochus |
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