A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2
Several mRNA-based vaccines for SARS-CoV-2 are in late phase clinical development. Here, the authors show that a single immunization with a mRNA vaccine expressing SARS-CoV-2 spike RBD induces neutralizing antibodies that are maintained for at least 6.5 months and confer protection in a sera transfe...
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Bibliographic Details
| Main Authors: |
Qingrui Huang,
Kai Ji,
Siyu Tian,
Fengze Wang,
Baoying Huang,
Zhou Tong,
Shuguang Tan,
Junfeng Hao,
Qihui Wang,
Wenjie Tan,
George F. Gao,
Jinghua Yan |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2021-02-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-21037-2
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