Polymorphisms of AZIN1 rs2679757 and TRPM5 rs886277 are Associated with Cirrhosis Risk in Chinese Patients with Chronic Hepatitis B

Objective Genome-wide association studies (GWAS) have linked many single nucleotide polymorphisms (SNPs) to the outcomes of a variety of liver diseases. The aim of the present study was to evaluate the association of several candidate SNPs with the risk and severity of cirrhosis due to chronic hepat...

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Main Authors: Peng Li-jun, Guo Jin-sheng, Zhang Zhe, Liu Li-li, Cao Yi-rong, Shi Hong, Wang Jian, Friedman Scott L., Sninsky John J., Wang Ji-yao
Format: Article
Language:English
Published: Sciendo 2012-06-01
Series:Infection International
Subjects:
Online Access:http://www.degruyter.com/view/j/ii.2012.1.issue-2/ii-2017-0016/ii-2017-0016.xml?format=INT
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spelling doaj-e390e81783da4eada0ce6e6b9f5cfb662020-11-24T21:08:00ZengSciendoInfection International2544-03492012-06-011210310910.1515/ii-2017-0016ii-2017-0016Polymorphisms of AZIN1 rs2679757 and TRPM5 rs886277 are Associated with Cirrhosis Risk in Chinese Patients with Chronic Hepatitis BPeng Li-jun0Guo Jin-sheng1Zhang Zhe2Liu Li-li3Cao Yi-rong4Shi Hong5Wang Jian6Friedman Scott L.7Sninsky John J.8Wang Ji-yao9Division of Digestive Diseases, Department of Internal Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, No.180 Feng Lin Road, Shanghai 200032, ChinaDivision of Digestive Diseases, Department of Internal Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, No.180 Feng Lin Road, Shanghai 200032, ChinaDivision of Digestive Diseases, Department of Internal Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, No.180 Feng Lin Road, Shanghai 200032, ChinaDivision of Digestive Diseases, Department of Internal Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, No.180 Feng Lin Road, Shanghai 200032, ChinaDivision of Digestive Diseases, Department of Internal Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, No.180 Feng Lin Road, Shanghai 200032, ChinaDivision of Digestive Diseases, Department of Internal Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, No.180 Feng Lin Road, Shanghai 200032, ChinaDivision of Digestive Diseases, Department of Internal Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, No.180 Feng Lin Road, Shanghai 200032, ChinaDivision of Liver Diseases, Mount Sinai School of Medicine, No.1425 Madison Ave, New York 10029, USACelera Corporation, Alameda, CA, USADivision of Digestive Diseases, Department of Internal Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, No.180 Feng Lin Road, Shanghai 200032, ChinaObjective Genome-wide association studies (GWAS) have linked many single nucleotide polymorphisms (SNPs) to the outcomes of a variety of liver diseases. The aim of the present study was to evaluate the association of several candidate SNPs with the risk and severity of cirrhosis due to chronic hepatitis B in a Chinese population.http://www.degruyter.com/view/j/ii.2012.1.issue-2/ii-2017-0016/ii-2017-0016.xml?format=INTHepatitis BCirrhosisSingle nucleotide polymorphismAntizyme inhibitor 1Transient receptor potential cation channel subfamily Mmember 5
collection DOAJ
language English
format Article
sources DOAJ
author Peng Li-jun
Guo Jin-sheng
Zhang Zhe
Liu Li-li
Cao Yi-rong
Shi Hong
Wang Jian
Friedman Scott L.
Sninsky John J.
Wang Ji-yao
spellingShingle Peng Li-jun
Guo Jin-sheng
Zhang Zhe
Liu Li-li
Cao Yi-rong
Shi Hong
Wang Jian
Friedman Scott L.
Sninsky John J.
Wang Ji-yao
Polymorphisms of AZIN1 rs2679757 and TRPM5 rs886277 are Associated with Cirrhosis Risk in Chinese Patients with Chronic Hepatitis B
Infection International
Hepatitis B
Cirrhosis
Single nucleotide polymorphism
Antizyme inhibitor 1
Transient receptor potential cation channel subfamily M
member 5
author_facet Peng Li-jun
Guo Jin-sheng
Zhang Zhe
Liu Li-li
Cao Yi-rong
Shi Hong
Wang Jian
Friedman Scott L.
Sninsky John J.
Wang Ji-yao
author_sort Peng Li-jun
title Polymorphisms of AZIN1 rs2679757 and TRPM5 rs886277 are Associated with Cirrhosis Risk in Chinese Patients with Chronic Hepatitis B
title_short Polymorphisms of AZIN1 rs2679757 and TRPM5 rs886277 are Associated with Cirrhosis Risk in Chinese Patients with Chronic Hepatitis B
title_full Polymorphisms of AZIN1 rs2679757 and TRPM5 rs886277 are Associated with Cirrhosis Risk in Chinese Patients with Chronic Hepatitis B
title_fullStr Polymorphisms of AZIN1 rs2679757 and TRPM5 rs886277 are Associated with Cirrhosis Risk in Chinese Patients with Chronic Hepatitis B
title_full_unstemmed Polymorphisms of AZIN1 rs2679757 and TRPM5 rs886277 are Associated with Cirrhosis Risk in Chinese Patients with Chronic Hepatitis B
title_sort polymorphisms of azin1 rs2679757 and trpm5 rs886277 are associated with cirrhosis risk in chinese patients with chronic hepatitis b
publisher Sciendo
series Infection International
issn 2544-0349
publishDate 2012-06-01
description Objective Genome-wide association studies (GWAS) have linked many single nucleotide polymorphisms (SNPs) to the outcomes of a variety of liver diseases. The aim of the present study was to evaluate the association of several candidate SNPs with the risk and severity of cirrhosis due to chronic hepatitis B in a Chinese population.
topic Hepatitis B
Cirrhosis
Single nucleotide polymorphism
Antizyme inhibitor 1
Transient receptor potential cation channel subfamily M
member 5
url http://www.degruyter.com/view/j/ii.2012.1.issue-2/ii-2017-0016/ii-2017-0016.xml?format=INT
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