Designing and Construction of a Multiepitope-Based DNA Vaccine to Induce Protective Immunity against Hepatitis C Virus

Designing and Construction of a Multiepitope-Based DNA Vaccine to Induce Protective Immunity against Hepatitis C Virus

Abstract Background: Hypervariability of hepatitis C virus (HCV) proteins is an important obstacle to design an efficient vaccine for the infection. To construct a protective vaccine against HCV, a DNA vaccine containing conserved epitopes of the virus was designed. To enhance the induced immune re...

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Bibliographic Details
Main Authors: Leila Pishraft Sabet, Katayoun Samimi Rad, Azam Bolhasani, Mahin Ahangar-Oskouee
Format: Article
Language:fas
Published: Arak Medical University 2016-04-01
Series:Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk
Subjects:
DNA Vaccine
Epitope
gp96
Hepatitis C virus
Online Access:http://amuj.arakmu.ac.ir/article-1-4056-en.pdf

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