A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support
Abstract Giant cell myocarditis is a rare but often devastating diagnosis. Advances in cardiac imaging and mechanical circulatory support have led to earlier and more frequent diagnoses and successful management. This disease state has wide variation in acuity of presentation, and consequently, opti...
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doaj-e40635ee84bf4bfb8d555a67b97ac1af2020-11-25T03:50:59ZengWileyESC Heart Failure2055-58222020-02-017131632010.1002/ehf2.12564A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory supportJulianne M. Fallon0Alex M. Parker1Steven P. Dunn2Jamie L.W. Kennedy3Department of Pharmacy Cleveland Clinic Cleveland OHDivision of Cardiology University of Florida Health Gainesville FL USADepartment of Pharmacy University of Virginia Health System Charlottesville VA USADivision of Cardiology University of California San Francisco San Francisco CA USAAbstract Giant cell myocarditis is a rare but often devastating diagnosis. Advances in cardiac imaging and mechanical circulatory support have led to earlier and more frequent diagnoses and successful management. This disease state has wide variation in acuity of presentation, and consequently, optimal treatment ranging from intensity and type of immunosuppression to mechanical circulatory support is not well defined. The following case describes the management of a patient with an unusual presentation of giant cell myocarditis over a 10 year course of advanced heart failure therapies and immunomodulatory support. This case highlights emerging concepts in the management of giant cell myocarditis including sub‐acute presentations, challenges in diagnosis, and treatment modalities in the modern era.https://doi.org/10.1002/ehf2.12564Giant cell myocarditismechanical circulatory supportimmunosuppression |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Julianne M. Fallon Alex M. Parker Steven P. Dunn Jamie L.W. Kennedy |
spellingShingle |
Julianne M. Fallon Alex M. Parker Steven P. Dunn Jamie L.W. Kennedy A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support ESC Heart Failure Giant cell myocarditis mechanical circulatory support immunosuppression |
author_facet |
Julianne M. Fallon Alex M. Parker Steven P. Dunn Jamie L.W. Kennedy |
author_sort |
Julianne M. Fallon |
title |
A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support |
title_short |
A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support |
title_full |
A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support |
title_fullStr |
A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support |
title_full_unstemmed |
A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support |
title_sort |
giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support |
publisher |
Wiley |
series |
ESC Heart Failure |
issn |
2055-5822 |
publishDate |
2020-02-01 |
description |
Abstract Giant cell myocarditis is a rare but often devastating diagnosis. Advances in cardiac imaging and mechanical circulatory support have led to earlier and more frequent diagnoses and successful management. This disease state has wide variation in acuity of presentation, and consequently, optimal treatment ranging from intensity and type of immunosuppression to mechanical circulatory support is not well defined. The following case describes the management of a patient with an unusual presentation of giant cell myocarditis over a 10 year course of advanced heart failure therapies and immunomodulatory support. This case highlights emerging concepts in the management of giant cell myocarditis including sub‐acute presentations, challenges in diagnosis, and treatment modalities in the modern era. |
topic |
Giant cell myocarditis mechanical circulatory support immunosuppression |
url |
https://doi.org/10.1002/ehf2.12564 |
work_keys_str_mv |
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1724489458703663104 |