Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort

Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort

Abstract Background Lung epithelial damage, activation of the wound healing cascade, and remodeling of the extracellular matrix (ECM) play a major role in chronic obstructive pulmonary disease (COPD). The pro-peptide of type VI collagen has been identified as the hormone endotrophin. Endotrophin has...

Full description

Bibliographic Details
Main Authors: Sarah R. Rønnow, Lasse L. Langholm, Morten A. Karsdal, Tina Manon-Jensen, Ruth Tal-Singer, Bruce E. Miller, Jørgen Vestbo, Diana J. Leeming, Jannie M. B. Sand
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Respiratory Research
Subjects:
COPD
Biomarkers
Extracellular matrix
Online Access:http://link.springer.com/article/10.1186/s12931-020-01461-6

Internet

http://link.springer.com/article/10.1186/s12931-020-01461-6

Similar Items