Hyaluronic acid injection therapy for osteoarthritis of the knee: concordant efficacy and conflicting serious adverse events in two systematic reviews

Hyaluronic acid injection therapy for osteoarthritis of the knee: concordant efficacy and conflicting serious adverse events in two systematic reviews

Abstract Background The prevalence of knee osteoarthritis (OA)/degenerative joint disease (DJD) is increasing in the USA. Systematic reviews of treatment efficacy and adverse events (AEs) of hyaluronic acid (HA) injections report conflicting evidence about the balance of benefits and harms. We revie...

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Bibliographic Details
Main Authors: Claire E. O’Hanlon, Sydne J. Newberry, Marika Booth, Sean Grant, Aneesa Motala, Margaret A. Maglione, John D. FitzGerald, Paul G. Shekelle
Format: Article
Language:English
Published: BMC 2016-11-01
Series:Systematic Reviews
Subjects:
Osteoarthritis, knee
Hyaluronic acid
Viscosupplementation
Adverse events
Online Access:http://link.springer.com/article/10.1186/s13643-016-0363-9

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