Characterization of a leukotriene C4 export mechanism in human platelets: possible involvement of multidrug resistance-associated protein 1

Platelets express leukotriene (LT) C4 synthase and can thus participate in the formation of bioactive LTC4. To further elucidate the relevance of this capability, we have now determined the capacity of human platelets to export LTC4. Endogenously formed LTC4 was efficiently released from human plate...

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Bibliographic Details
Main Authors: Mikael Sjölinder, Susanne Tornhamre, Hans-Erik Claesson, Jonas Hydman, Jan Åke Lindgren
Format: Article
Language:English
Published: Elsevier 1999-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520324482