miR-103 promotes endothelial maladaptation by targeting lncWDR59

MicroRNAs play important roles in endothelial cells injury, proliferation and maladaptation by negatively regulating posttranscriptional gene expression. Here the authors uncover the role of the long non coding RNA lncWDR59, target of miR-103, in endothelial maladaptation.

Bibliographic Details
Main Authors: Lucia Natarelli, Claudia Geißler, Gergely Csaba, Yuanyuan Wei, Mengyu Zhu, Andrea di Francesco, Petra Hartmann, Ralf Zimmer, Andreas Schober
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05065-z
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spelling doaj-e46a8034cfe74cfca27a2a286f3200ff2021-05-11T09:48:37ZengNature Publishing GroupNature Communications2041-17232018-07-019111510.1038/s41467-018-05065-zmiR-103 promotes endothelial maladaptation by targeting lncWDR59Lucia Natarelli0Claudia Geißler1Gergely Csaba2Yuanyuan Wei3Mengyu Zhu4Andrea di Francesco5Petra Hartmann6Ralf Zimmer7Andreas Schober8Experimental Vascular Medicine, Institute for Cardiovascular Prevention, Ludwig-Maximilians University MunichExperimental Vascular Medicine, Institute for Cardiovascular Prevention, Ludwig-Maximilians University MunichInstitute for Informatics, Ludwig-Maximilians University MunichExperimental Vascular Medicine, Institute for Cardiovascular Prevention, Ludwig-Maximilians University MunichExperimental Vascular Medicine, Institute for Cardiovascular Prevention, Ludwig-Maximilians University MunichExperimental Vascular Medicine, Institute for Cardiovascular Prevention, Ludwig-Maximilians University MunichExperimental Vascular Medicine, Institute for Cardiovascular Prevention, Ludwig-Maximilians University MunichInstitute for Informatics, Ludwig-Maximilians University MunichExperimental Vascular Medicine, Institute for Cardiovascular Prevention, Ludwig-Maximilians University MunichMicroRNAs play important roles in endothelial cells injury, proliferation and maladaptation by negatively regulating posttranscriptional gene expression. Here the authors uncover the role of the long non coding RNA lncWDR59, target of miR-103, in endothelial maladaptation.https://doi.org/10.1038/s41467-018-05065-z
collection DOAJ
language English
format Article
sources DOAJ
author Lucia Natarelli
Claudia Geißler
Gergely Csaba
Yuanyuan Wei
Mengyu Zhu
Andrea di Francesco
Petra Hartmann
Ralf Zimmer
Andreas Schober
spellingShingle Lucia Natarelli
Claudia Geißler
Gergely Csaba
Yuanyuan Wei
Mengyu Zhu
Andrea di Francesco
Petra Hartmann
Ralf Zimmer
Andreas Schober
miR-103 promotes endothelial maladaptation by targeting lncWDR59
Nature Communications
author_facet Lucia Natarelli
Claudia Geißler
Gergely Csaba
Yuanyuan Wei
Mengyu Zhu
Andrea di Francesco
Petra Hartmann
Ralf Zimmer
Andreas Schober
author_sort Lucia Natarelli
title miR-103 promotes endothelial maladaptation by targeting lncWDR59
title_short miR-103 promotes endothelial maladaptation by targeting lncWDR59
title_full miR-103 promotes endothelial maladaptation by targeting lncWDR59
title_fullStr miR-103 promotes endothelial maladaptation by targeting lncWDR59
title_full_unstemmed miR-103 promotes endothelial maladaptation by targeting lncWDR59
title_sort mir-103 promotes endothelial maladaptation by targeting lncwdr59
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-07-01
description MicroRNAs play important roles in endothelial cells injury, proliferation and maladaptation by negatively regulating posttranscriptional gene expression. Here the authors uncover the role of the long non coding RNA lncWDR59, target of miR-103, in endothelial maladaptation.
url https://doi.org/10.1038/s41467-018-05065-z
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