Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay

Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay

To date the carboacylation of alkenes has been reported only in single- and two-component methodologies. Here, the authors report a three-component nickel-catalyzed carboacylation of olefins which enables the rapid construction of ketones with high levels of complexity and diversity.

Bibliographic Details
Main Authors: Xian Zhao, Hai-Yong Tu, Lei Guo, Shengqing Zhu, Feng-Ling Qing, Lingling Chu
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05951-6
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spelling doaj-e47c110e45244dd8aba2aefe8589ec402021-05-11T09:45:26ZengNature Publishing GroupNature Communications2041-17232018-08-01911710.1038/s41467-018-05951-6Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relayXian Zhao0Hai-Yong Tu1Lei Guo2Shengqing Zhu3Feng-Ling Qing4Lingling Chu5State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityTo date the carboacylation of alkenes has been reported only in single- and two-component methodologies. Here, the authors report a three-component nickel-catalyzed carboacylation of olefins which enables the rapid construction of ketones with high levels of complexity and diversity.https://doi.org/10.1038/s41467-018-05951-6
collection DOAJ
language English
format Article
sources DOAJ
author Xian Zhao
Hai-Yong Tu
Lei Guo
Shengqing Zhu
Feng-Ling Qing
Lingling Chu
spellingShingle Xian Zhao
Hai-Yong Tu
Lei Guo
Shengqing Zhu
Feng-Ling Qing
Lingling Chu
Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay
Nature Communications
author_facet Xian Zhao
Hai-Yong Tu
Lei Guo
Shengqing Zhu
Feng-Ling Qing
Lingling Chu
author_sort Xian Zhao
title Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay
title_short Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay
title_full Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay
title_fullStr Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay
title_full_unstemmed Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay
title_sort intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-08-01
description To date the carboacylation of alkenes has been reported only in single- and two-component methodologies. Here, the authors report a three-component nickel-catalyzed carboacylation of olefins which enables the rapid construction of ketones with high levels of complexity and diversity.
url https://doi.org/10.1038/s41467-018-05951-6
work_keys_str_mv AT xianzhao intermolecularselectivecarboacylationofalkenesvianickelcatalyzedreductiveradicalrelay
AT haiyongtu intermolecularselectivecarboacylationofalkenesvianickelcatalyzedreductiveradicalrelay
AT leiguo intermolecularselectivecarboacylationofalkenesvianickelcatalyzedreductiveradicalrelay
AT shengqingzhu intermolecularselectivecarboacylationofalkenesvianickelcatalyzedreductiveradicalrelay
AT fenglingqing intermolecularselectivecarboacylationofalkenesvianickelcatalyzedreductiveradicalrelay
AT linglingchu intermolecularselectivecarboacylationofalkenesvianickelcatalyzedreductiveradicalrelay
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