Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay
To date the carboacylation of alkenes has been reported only in single- and two-component methodologies. Here, the authors report a three-component nickel-catalyzed carboacylation of olefins which enables the rapid construction of ketones with high levels of complexity and diversity.
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2018-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05951-6 |
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doaj-e47c110e45244dd8aba2aefe8589ec402021-05-11T09:45:26ZengNature Publishing GroupNature Communications2041-17232018-08-01911710.1038/s41467-018-05951-6Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relayXian Zhao0Hai-Yong Tu1Lei Guo2Shengqing Zhu3Feng-Ling Qing4Lingling Chu5State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityTo date the carboacylation of alkenes has been reported only in single- and two-component methodologies. Here, the authors report a three-component nickel-catalyzed carboacylation of olefins which enables the rapid construction of ketones with high levels of complexity and diversity.https://doi.org/10.1038/s41467-018-05951-6 |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xian Zhao Hai-Yong Tu Lei Guo Shengqing Zhu Feng-Ling Qing Lingling Chu |
spellingShingle |
Xian Zhao Hai-Yong Tu Lei Guo Shengqing Zhu Feng-Ling Qing Lingling Chu Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay Nature Communications |
author_facet |
Xian Zhao Hai-Yong Tu Lei Guo Shengqing Zhu Feng-Ling Qing Lingling Chu |
author_sort |
Xian Zhao |
title |
Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay |
title_short |
Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay |
title_full |
Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay |
title_fullStr |
Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay |
title_full_unstemmed |
Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay |
title_sort |
intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2018-08-01 |
description |
To date the carboacylation of alkenes has been reported only in single- and two-component methodologies. Here, the authors report a three-component nickel-catalyzed carboacylation of olefins which enables the rapid construction of ketones with high levels of complexity and diversity. |
url |
https://doi.org/10.1038/s41467-018-05951-6 |
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