Quantitative assays reveal cell fusion at minimal levels of SARS-CoV-2 spike protein and fusion from without

Quantitative assays reveal cell fusion at minimal levels of SARS-CoV-2 spike protein and fusion from without

Summary: Cell entry of the pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by its spike protein S. As a main antigenic determinant, S protein is in focus of various therapeutic strategies. Besides particle-cell fusion, S mediates fusion between infected and uninfect...

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Bibliographic Details
Main Authors: Samuel A. Theuerkauf, Alexander Michels, Vanessa Riechert, Thorsten J. Maier, Egbert Flory, Klaus Cichutek, Christian J. Buchholz
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Membrane Architecture
Cell Biology
Biochemical Assay
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221001383

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