Nociceptor Signalling through ion Channel Regulation via GPCRs

Nociceptor Signalling through ion Channel Regulation via GPCRs

The prime task of nociceptors is the transformation of noxious stimuli into action potentials that are propagated along the neurites of nociceptive neurons from the periphery to the spinal cord. This function of nociceptors relies on the coordinated operation of a variety of ion channels. In this re...

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Bibliographic Details
Main Authors: Isabella Salzer, Sutirtha Ray, Klaus Schicker, Stefan Boehm
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
nociceptor
inflammatory pain
G protein-coupled receptor
voltage-gated ion channel
TRP channel
K<sub>2<i>P</i></sub> channel
Ca<sup>2+</sup>-activated Cl<sup>−</sup> channel
Online Access:https://www.mdpi.com/1422-0067/20/10/2488

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