Clinical Characteristics and Prognostic Factors of 35 Patients with Esophagus Adenoid Cystic Carcinoma Patients

• Main Authors: ZHANG Guoliang, ZENG Hui, WANG Tao, ZHU Qikun, ZHANG Dandan, WANG Rui
• Format: Article
• Language: zho
• Published: Magazine House of Cancer Research on Prevention and Treatment 2018-04-01
• Series: Zhongliu Fangzhi Yanjiu
• Subjects: esophagus cancer; adenoid cystic carcinoma; surgery; prognosis
• Online Access: http://html.rhhz.net/ZLFZYJ/html/8578.2018.17.0627.htm

Objective To analyze the clinical characteristics, diagnosis, treatment and prognosis of the esophagus adenoid cystic carcinoma(EACC). Methods We collected the clinical data of 35 patients treated with surgical resection of underlying tumors and pathologically confirmed as EACC. Clinicopathologic characteristics and prognostic factors were analyzed. Results EACC was commonly observed at middle-esophagus, with an average age of 60.6 years old and male-to-female ratio of 4:1. The major pathological type of EACC was umbrella and polypoid. EACC was less frequently accompanied by nerve invasion, especially at the early stage. The recurrence and metastasis rates were higher in solid tumors than those in cribriform tumors. The median survival time was 38 months, and the average 1-, 3-and 5-year survival rates were 88.1%, 46.6% and 27.1%, respectively. Conclusion Adenoid cystic carcinoma(ACC) is a very rare malignant tumor in the esophagus. The tumor size and pathological stage are related to the prognosis of EACC.