p16, Cyclin D1, and HIF-1α Predict Outcomes of Patients with Oropharyngeal Squamous Cell Carcinoma Treated with Definitive Intensity-Modulated Radiation Therapy
We evaluated a panel of 8 immunohistochemical biomarkers as predictors of clinical response to definitive intensity-modulated radiotherapy in patients with oropharyngeal squamous cell carcinoma (OPSCC). 106 patients with OPSCC were treated to a total dose of 66–70 Gy and retrospectively analyzed for...
Main Authors: | Asal S. Rahimi, David D. Wilson, Drew K. Saylor, Edward B. Stelow, Christopher Y. Thomas, James F. Reibel, Paul A. Levine, David C. Shonka, Mark J. Jameson, Paul W. Read |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
|
Series: | International Journal of Otolaryngology |
Online Access: | http://dx.doi.org/10.1155/2012/685951 |
Similar Items
-
Prognostic significance of LINE-1 hypomethylation in oropharyngeal squamous cell carcinoma
by: Carlo Furlan, et al.
Published: (2017-05-01) -
KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia
by: Rajnish Kumar Singh, et al.
Published: (2021-07-01) -
Expression of cyclin D1 in oral squamous cell carcinoma
by: Lin, Chiao-Ying, et al.
Published: (1997) -
Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma
by: Michaela Plath, et al.
Published: (2018-09-01) -
Glyoxalase 1 expression is associated with an unfavorable prognosis of oropharyngeal squamous cell carcinoma
by: Nele Kreycy, et al.
Published: (2017-05-01)