Correlation between Cyclin Dependent Kinases and Artemisinin-Induced Dormancy in Plasmodium falciparum In Vitro.

Correlation between Cyclin Dependent Kinases and Artemisinin-Induced Dormancy in Plasmodium falciparum In Vitro.

Artemisinin-induced dormancy provides a plausible explanation for recrudescence following artemisinin monotherapy. This phenomenon shares similarities with cell cycle arrest where cyclin dependent kinases (CDKs) and cyclins play an important role.Transcription profiles of Plasmodium falciparum CDKs...

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Bibliographic Details
Main Authors: Karen-Ann Gray, Karryn J Gresty, Nanhua Chen, Veronica Zhang, Clare E Gutteridge, Christopher L Peatey, Marina Chavchich, Norman C Waters, Qin Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4915707?pdf=render

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