Malignant Degeneration of Scars

• Main Authors: Chiriac AE, Betiu M, Brzezinski P, Di Martino Ortiz B, Chiriac A, Foia L, Azoicai D
• Format: Article
• Language: English
• Published: Dove Medical Press 2020-10-01
• Series: Cancer Management and Research
• Subjects: ulcer; marjolin; malignant degeneration; scar
• Online Access: https://www.dovepress.com/malignant-degeneration-of-scars-peer-reviewed-article-CMAR

Anca E Chiriac,1 Mircea Betiu,2 Piotr Brzezinski,3,4 Beatriz Di Martino Ortiz,5 Anca Chiriac,6– 8 Liliana Foia,9 Doina Azoicai1 1Department of Epidemiology, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania; 2Department of Dermatovenereology, Faculty of Medicine, “Nicolae Testemitanu” State University of Medicine and Pharmacy, Kishinev, Republic of Moldova; 3Department of Physiology and Cosmetology, Institute of Biology and Environmental Protection, Pomeranian Academy, Slupsk, Poland; 4Department of Dermatology, Provincial Specialist Hospital in Slupsk, Ustka, Poland, Military Support Unit, Ustka, Poland; 5Dermatology Department, Clinicas Hospital, Faculty of Medical Sciences, National University of Ausunción-Paraguay; 6Department of Dermatology, Nicolina Medical Center, Iasi, Romania; 7Department of Dermatophysiology, “Apollonia” University, Iasi, Romania; 8“P.poni” Insitute of Macromolecular Chemistry, Romanian Academy, Iasi, Romania; 9Department of Surgery, Faculty of Dentistry, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaCorrespondence: Anca E ChiriacDepartment of Epidemiology, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaEmail [e-mail]: ”Marjolin’s ulcer” is known as malignant degeneration of ancient burn scars, but both words can induce misdiagnosis. Malignant degeneration of scarring tissue can occur and can vary in its clinical, histological manifestations and its pre-existing skin lesions. We present several cases to substantiate our observations. ”Marjolin’s ulcer” is not synonym to an ulceration appeared on an old burn scar, transformed into squamous cell carcinoma.Keywords: ulcer, Marjolin, malignant degeneration, scar